FITC标记的丝氨酸/精氨酸相关核基质蛋白4抗体
产品名称： FITC标记的丝氨酸/精氨酸相关核基质蛋白4抗体
英文名称： Anti-SRRM4/FITC
产品编号： HZ-8069R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-SRRM4/FITC Conjugated antibody
FITC标记的丝氨酸/精氨酸相关核基质蛋白4抗体
| 英文名称 | Anti-SRRM4/FITC |
| 中文名称 | FITC标记的丝氨酸/精氨酸相关核基质蛋白4抗体 |
| 别 名 | Neural-specific serine/arginine repetitive splicing factor of 100 kDa; Neural-specific SR-related protein of 100 kDa; nSR100; Serine/arginine repetitive matrix protein 4; Srrm4; SRRM4_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 发育生物学 神经生物学 信号转导 细胞周期蛋白 细胞分化 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Chicken, Dog, Cow, Sheep, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 69kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human SRRM4 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Splicing factor specifically required for neural cell differentiation. Acts in conjuction with nPTB/PTBP2 by binding directly to its regulated target transcripts and promotes neural-specific exon inclusion in many genes that function in neural cell differentiation. Required to promote the inclusion of neural-specific exon 10 in nPTB/PTBP2, leading to increased expression of neural-specific nPTB/PTBP2. Also promotes the inclusion of exon 16 in DAAM1 in neuron extracts. Function: Splicing factor specifically required for neural celldifferentiation. Acts in conjuction with nPTB/PTBP2 by bindingdirectly to its regulated target transcripts and promotesneural-specific exon inclusion in many genes that function inneural cell differentiation. Required to promote the inclusion ofneural-specific exon 10 in nPTB/PTBP2, leading to increasedexpression of neural-specific nPTB/PTBP2. Also promotes theinclusion of exon 16 in DAAM1 in neuron extracts (By similarity). Subcellular Location: Nucleus (By similarity). Tissue Specificity: Specifically expressed in neuronal cells (atprotein level). Expressed in the cerebellum. Post-translational modifications: Phosphorylated (By similarity). Similarity: Belongs to the nSR100 family. Database links: UniProtKB/Swiss-Prot: A7MD48.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
剪接因子特别需要神经细胞分化。与NPTB/PTBP2结合，直接结合其调节的靶转录，并促进神经特异性外显子包含在许多神经细胞分化的基因中。需要促进神经特异性外显子10在NPTB/PTBP2中的加入，导致神经特异性NPTB/PTBP2表达增加。还可促进神经元中的DAAM1中第16外显子的导入。