FITC标记的癌/睾丸抗原11.4抗体
产品名称： FITC标记的癌/睾丸抗原11.4抗体
英文名称： Anti-SPANXD/CT11.4/FITC
产品编号： HZ-17621R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-SPANXD/CT11.4/FITC Conjugated antibody
FITC标记的癌/睾丸抗原11.4抗体
| 英文名称 | Anti-SPANXD/CT11.4/FITC |
| 中文名称 | FITC标记的癌/睾丸抗原11.4抗体 |
| 别 名 | Cancer/testis antigen 11.4; Cancer/testis antigen family 11 member 4; CT11.4; dJ171K16.1; Nuclear associated protein SPAN Xd; Nuclear-associated protein SPAN-Xd; SPAN Xd protein; SPANX C; SPANX D; SPANX family member D; SPANX-D; SPANXD; Sperm protein associated with the nucleus on the X chromosome D; Sperm protein associated with the nucleus X chromosome family member D; SPNXD_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 细胞生物 发育生物学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 11kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human SPANXD/CT11.4 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Temporally regulated transcription and translation of several testis-specific genes is required to initiate the series of molecular and morphological changes in the male germ cell lineage necessary for the formation of mature spermatozoa. This gene is a member of the SPANX family of cancer/testis-associated genes, which are located in a cluster on chromosome X. The SPANX genes encode differentially expressed testis-specific proteins that localize to various subcellular compartments. This particular gene encodes a sperm protein that is associated with the nucleus but, although a role in spermatogenesis is suggested, the specific function of this family member has not yet been determined. Polymorphisms in this gene may be associated with prostate cancer susceptibility. [provided by RefSeq, Apr 2014] Subcellular Location: Cytoplasm. Nucleus. Associated with nuclear craters. Tissue Specificity: Detected in testis, sperm and a melanoma cell line. Similarity: Belongs to the SPAN-X family. Database links: Entrez Gene: 64648 Human Omim: 300670 Human SwissProt: Q9BXN6 Human Unigene: 375036 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
一些睾丸特异性基因的转录和翻译需要时间调控，以启动成熟精子形成所必需的雄性生殖细胞谱系的一系列分子和形态学改变。该基因是SPANX家族的癌症/睾丸相关基因的成员，位于X染色体上的一个簇。这个特殊的基因编码一个与细胞核相关的精子蛋白，但是，尽管有人建议它在精子发生中起作用，但是这个家族成员的具体功能尚未确定。该基因的多态性可能与前列腺癌相关。