FITC标记的囊性组织液体蛋白15抗体
产品名称： FITC标记的囊性组织液体蛋白15抗体
英文名称： Anti-GCDGP15/FITC
产品编号： HZ-3795R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-GCDGP15/FITC Conjugated antibody
FITC标记的囊性组织液体蛋白15抗体
| 英文名称 | Anti-GCDGP15/FITC |
| 中文名称 | FITC标记的囊性组织液体蛋白15抗体 |
| 别 名 | GCDGP15; GCDGP 15; GCDGP-15; Gp17; GPIP4; Gross cystic disease fluid protein 15; Prolactin induced protein; Prolactin inducible protein precursor; SABP; Secretory actin binding protein.PIP_HUMAN |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 细胞生物 免疫学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 13.5kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human GCDGP15/SABP |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Gross cystic disease is a common premenopausal disorder in which gross cysts are the predominant pathologic lesion. It is characterized by production of a fluid secretion which accumulates in the breast cysts. Gross cystic disease fluid is a pathologic secretion from breast composed of several glycoproteins, including a unique 15 kDa monomer protein, GCDFP 15. The cells within the body that produce GCDFP 15 appear to be restricted primarily to those with apocrine function. Studies have found GCDFP 15 to be a highly specific and sensitive marker for breast cancer. Subunit: Monomer. Interacts with AZGP1. Subcellular Location: Secreted. Tissue Specificity: Expressed in pathological conditions of the mammary gland and in several exocrine tissues, such as the lacrimal, salivary, and sweat glands. Similarity: Belongs to the PIP family. Database links: Entrez Gene: 5304 Human Omim: 176720 Human SwissProt: P12273 Human Unigene: 99949 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. GCDFP15是一种15kDa的单链蛋白，常见于组织囊性病变的囊泡液中。GCDFP-15是一种高度特异和敏感的乳腺癌标志，可用于乳腺癌的鉴别诊断，与CK7和CK20联合使用，可以用于鉴别原发或继发乳腺外派杰氏病 |
囊性疾病是一种常见的绝经前疾病，其中囊肿是主要的病理损害。它的特点是分泌一种分泌在乳腺囊肿中的液体分泌物。粗囊性疾病液是由几种糖蛋白组成的乳腺的病理分泌物，包括独特的15 kDa单体蛋白GCDFP 15。体内产生GCDFP 15的细胞似乎主要局限于具有顶浆功能的细胞。研究发现GCDFP 15是一个高度特异和敏感的乳腺癌标志物。