PeproTech Armenian Hamster抗小鼠CD152(CTLA-4) PE-Cy7
产品名称： PeproTech Armenian Hamster抗小鼠CD152(CTLA-4) PE-Cy7
英文名称： Anti-Mouse CD152 (CTLA-4) PE-Cy7
产品编号： 14612-77-100
产品价格： null
产品产地： USA
品牌商标： peperotech(BioGems)
更新时间： null
使用范围： 流式
美国PeproTech(派普泰克)公司中国代表处
- 联系人 :
- 地址 :  江苏省苏州市工业园区星湖街218号A1北座4楼L03
- 邮编 : 215123
- 所在区域 : 江苏
- 电话 : 点击查看
- 传真 : 点击查看
- 邮箱 : peprotech.infochina@thermofisher.com
The UC10-4F10-11 monoclonal antibody specifically reacts with the mouse Cytotoxic T-Lymphocyte Antigen-4 (CTLA-4), also known as CD152. It is a protein with a structure similar to CD28 regarding the genomic organization, amino acid sequence, and structure. CTLA-4 is expressed on activated T cells and CD25+/CD4+ Treg lymphocytes and binds the members of the B7 family, B7-1 (CD80) and B7-2 (CD86), with higher affinity than CD28. CD28 seems to provide opposing signal to T lymphocytes, while CD152 inhibits the T lymphocytes progression to an activated state and their proliferation, CD28 is a costimulator. The mouse UC10 -4F10-11 monoclonal antibody does not cross-react with the rat leukocytes.