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上海信裕生物科技有限公司
CD47抗体

CD47抗体

商家询价

产品名称： CD47抗体

英文名称： CD47Antibody

产品编号： XY20305-1

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

上海信裕生物科技有限公司
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 CD47抗体

Applications
In-house applications ELISA, WB, IHC     Application not tested? Please see our Guarantee.
Species specificity Human; other species not tested.
Images
Prev1NextView more validation data
  • 20305-1-AP;Jurkat cellJurkat cells were subjected to SDS PAGE followed by western blot with 20305-1-AP(CD47 antibody) at dilution of 1:500
  • 20305-1-AP;human ovary tumor tissueImmunohistochemistry of paraffin-embedded human ovary tumor tissue slide using 20305-1-AP( CD47 Antibody) at dilution of 1:200 (under 10x lens). heat mediated antigen retrieved with Tris-EDTA buffer(pH9).
  • 20305-1-AP;human ovary tumor tissueImmunohistochemistry of paraffin-embedded human ovary tumor tissue slide using 20305-1-AP( CD47 Antibody) at dilution of 1:200 (under 40x lens). heat mediated antigen retrieved with Tris-EDTA buffer(pH9).
Positive WB detected in Jurkat cells
Positive IHC detected in Human ovary tumor tissue
Recommended dilution WB : 1:200-1:2000
IHC : 1:50-1:500
 CD47抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information
Immunogen CD47 fusion protein ag14132 Full name CD47 molecule
Calculated molecular
weight		 323aa,35 kDa Observed molecular 
weight		 47-55 kDa
GenBank accession 
number		 BC010016 Gene ID (NCBI) 961
Gene symbol CD47 Synonyms CD47, CD47 molecule, IAP, Leukocyte surface antigen CD47, MER6, OA3, Protein MER6
Background CD47抗体

CD47, also known as integrin-associated protein (IAP), is a member of the immunoglobulin superfamily containing a five-pass transmembrane attachment. CD47 is heavily glycosylated and widely expressed by hematopoietic and nonhematopoietic cells. CD47 interacts with several membrane integrins and also acts a receptor for thrombospondin (THBS1). It is involved in a range of cellular processes, including apoptosis, proliferation, adhesion, and migration. CD47 also functions as a ligand for signal regulatory protein-α (SIRPα). Upon binding CD47, SIRPα initiates a signaling cascade that results in the inhibition of phagocytosis. CD47抗体

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