BCLAF1,Bcl2相关转录因子抗体

产品编号HZ-7583R
英文名称BCLAF1
中文名称Bcl2相关转录因子抗体
别 名Bcl 2 associated transcription factor; Bcl-2-associated transcription factor 1; BCL2 associated transcription factor 1; BCLAF1; BCLF1_HUMAN; Btf.
说 明 书0.1ml 0.2ml
研究领域细胞生物 细胞凋亡 转录调节因子 表观遗传学
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Dog, Cow, Horse, Sheep,
BCLAF1,Bcl2相关转录因子抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量106kDa
细胞定位细胞核 细胞浆
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human BTF/BCLAF1 (305-340aa)
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
BCLAF1,Bcl2相关转录因子抗体PubMedPubMed
产品介绍background:
This gene encodes a transcriptional repressor that interacts with several members of the BCL2 family of proteins. Overexpression of this protein induces apoptosis, which can be suppressed by co-expression of BCL2 proteins. The protein localizes to dot-like structures throughout the nucleus, and redistributes to a zone near the nuclear envelope in cells undergoing apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene.

Function:
Death-promoting transcriptional repressor.

Subunit:
Interacts with Bcl-2 related proteins, EMD, with the adenovirus E1B 19 kDa protein and with DNA.

Subcellular Location:
Cytoplasm. Nucleus.

BCLAF1,Bcl2相关转录因子抗体Tissue Specificity:
Ubiquitous.

Database links:
UniProtKB/Swiss-Prot: Q9NYF8.2

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.