Fibrinogen beta chain 抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
Fibrinogen beta chain 抗体

Fibrinogen beta chain 抗体

商家询价

产品名称： Fibrinogen beta chain 抗体

英文名称： Fibrinogen beta chain Antibody

产品编号： XY16747-1

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

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 FIBRINOGEN BETA CHAIN 抗体

Applications
In-house applications ELISA, WB, IHC     Application not tested? Please see our Guarantee.
Published applications IF, IHC Publications 1 citations –view here
Species specificity Human,Mouse,Rat; other species not tested.
Published Species Human, rat
Images
Prev1NextView more validation data
  • 16747-1-AP;mouse heart tissuemouse heart tissue were subjected to SDS PAGE followed by western blot with 16747-1-AP(FGB antibody) at dilution of 1:1000
  • 16747-1-AP;H-kidneyImmunohistochemical of paraffin-embedded human kidney using 16747-1-AP(FGB antibody) at dilution of 1:50 (under 10x lens)
  • 16747-1-AP;H-kidneyImmunohistochemical of paraffin-embedded human kidney using 16747-1-AP(FGB antibody) at dilution of 1:50 (under 40x lens)
Positive WB detected in Mouse heart tissue, mouse brain tissue, mouse kidney tissue, mouse liver tissue
Positive IHC detected in Human kidney tissue
Recommended dilution WB : 1:500-1:5000
IHC : 1:20-1:200
 FIBRINOGEN BETA CHAIN 抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information
Immunogen Fibrinogen beta chain fusion protein ag10169 Full name Fibrinogen beta chain
Calculated molecular
weight		 491aa,56 kDa Observed molecular 
weight		 47-56 kDa
GenBank accession 
number		 BC107766 Gene ID (NCBI) 2244
Gene symbol FGB Synonyms FGB, fibrinogen beta chain
Background FIBRINOGEN BETA CHAIN 抗体

Fibrinogen is a soluble plasma glycoprotein synthesized in the liver. It is composed of two sets of three structurally different subunits: alpha (FGA), beta (FGB), gamma (FGG). Fibrinogen is converted by thrombin into fibrin during blood coagulation. Fibrinogen and fibrin play overlapping roles in blood clotting, fibrinolysis, cellular and matrix interactions, the inflammatory response, wound healing, and neoplasia (PMID: 16102057). FGB is the beta chain of fibrinogen. During conversion of fibrinogen to fibrin, fibrinopeptide B is cleaved from FGB by thrombin. Mutations in the gene of FGB lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency. FIBRINOGEN BETA CHAIN 抗体

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