OGT 抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
OGT 抗体

OGT 抗体

商家询价

产品名称： OGT 抗体

英文名称： OGT Antibody

产品编号： XY 11576-2

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

上海信裕生物科技有限公司
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 OGT 抗体Applications

In-house applications ELISA, WB, IHC, IP     Application not tested? Please see our Guarantee.
Published applications IHC, WB Publications 5 citations –view here
Species specificity Human,Mouse,Rat; other species not tested.
Published Species Human, mouse
Images
Prev1NextView more validation data
  • 11576-2-AP;human pancreas cancerImmunohistochemical of paraffin-embedded human pancreas cancer using 11576-2-AP(OGT antibody) at dilution of 1:50 (under 10x lens)
  • 11576-2-AP;mouse brain tissueIP Result of anti-OGT (IP:11576-2-AP, 3ug; Detection:11576-2-AP 1:1000) with mouse brain tissue lysate 8000ug.
  • 11576-2-AP;human brain tissuehuman brain tissue were subjected to SDS PAGE followed by western blot with 11576-2-AP(OGT antibody) at dilution of 1:500
Positive WB detected in Human brain tissue, human liver tissue, mouse brain tissue, mouse liver tissue, rat brain tissue
Positive IP detected in Mouse brain tissue
Positive IHC detected in Human pancreas cancer tissue
Recommended dilution WB : 1:500-1:5000
IP : 1:500-1:5000
IHC : 1:20-1:200
 OGT 抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information
Immunogen OGT fusion protein ag2160 Full name O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)
Calculated molecular
weight		 1046aa,117 kDa Observed molecular 
weight		 110kd
GenBank accession 
number		 BC014434 Gene ID (NCBI) 8473
Gene symbol OGT Synonyms HRNT1, O GLCNAC, OGT
Background OGT 抗体

O-linked N-acetylglucosamine transferase (OGT) catalyzes the attachment of N-acetylglucosamine (GlcNAc) monosaccharides to the hydroxyl group of serine or threonine residues of numerous nuclear and cytoplasmic proteins and may play important roles in a large number of diverse intracellular processes ranging from translational control, transcription, transcriptional repression, insulin resistance and regulation of the cell cycle. It exists as a heterotrimeric complex with two 110 kDa and one 70 kDa subunits. Recent studies have shown that O-GlcNAcylation plays essential roles in cancer formation and progression. O-GlcNAcylation as well as OGT expression was found to be significantly elevated in the cancer tissues. OGT 抗体

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