GAP43抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
GAP43抗体

GAP43抗体

商家询价

产品名称： GAP43抗体

英文名称： GAP43Antibody

产品编号： XY16971-1

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

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 GAP43抗体

Applications
In-house applications ELISA, WB, IP     Application not tested? Please see our Guarantee.
Published applications IHC Publications 1 citations –view here
Species specificity Human,Mouse,Rat; other species not tested.
Published Species Rat
Images
Prev1NextView more validation data
  • 16971-1-AP;mouse brain tissuemouse brain tissue were subjected to SDS PAGE followed by western blot with 16971-1-AP(GAP43 antibody) at dilution of 1:1200
  • 16971-1-AP;mouse brain tissueIP Result of anti-GAP43 (IP:16971-1-AP, 4ug; Detection:16971-1-AP 1:500) with mouse brain tissue lysate 6000ug.
Positive WB detected in Mouse brain tissue, rat brain tissue, rat lung tissue
Positive IP detected in Mouse brain tissue
Recommended dilution WB : 1:500-1:5000
IP : 1:200-1:2000
 GAP43抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information
Immunogen GAP43 fusion protein ag9294 Full name Growth associated protein 43
Calculated molecular
weight		 238aa,25 kDa Observed molecular 
weight		 43 kDa
GenBank accession 
number		 BC007936 Gene ID (NCBI) 2596
Gene symbol GAP43 Synonyms Axonal membrane protein GAP 43, B 50, GAP43, growth associated protein 43, Neural phosphoprotein B 50, Neuromodulin, PP46
Background GAP43抗体

The neuronal growth-associated protein GAP43 is also known as neuromodulin, B-50, P-57, F1 and pp46. Deficiency of GAP43 in mice results in death early in the postnatal period. GAP43 is one of the main substrates for protein kinase C in the brain. GAP43 is an intracellular growth-associated protein that appears to assist neuronal pathfinding and branching during development and regeneration, and may contribute to presynaptic membrane changes in the adult, leading to the neurotransmitter release, endocytosis and synaptic vesicle recycling, long-term potentiation, spatial memory formation, and learning. The predicated molecular weight of about 25 kDa is much lower than the apparent observed molecular weight of 43 kDa on SDS-PAGE gels, and this occurs because the highly charged nature of GAP43 causes it to bind less than the average amount of SDS per amino acid, and because the protein has an elongated structure. GAP43抗体

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