FITC标记的含纤维蛋白原C结构域蛋白1抗体
产品名称： FITC标记的含纤维蛋白原C结构域蛋白1抗体
英文名称： Anti-FIBCD1/FITC
产品编号： HZ-9546R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-FIBCD1/FITC Conjugated antibody
FITC标记的含纤维蛋白原C结构域蛋白1抗体
| 产品编号 | bs-9546R-FITC |
| 英文名称 | Anti-FIBCD1/FITC |
| 中文名称 | FITC标记的含纤维蛋白原C结构域蛋白1抗体 |
| 别 名 | FIBCD 1; Fibrinogen C domain containing 1; Fibrinogen C domain containing protein 1; FLJ14810; FBCD1_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 免疫学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Pig, Cow, Zebrafish, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 51kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human FIBCD1 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: FIBCD1 is a 461 amino acid single-pass membrane protein that contains one fibrinogen C-terminal domain and exists as multiple alternatively spliced isoforms. The gene encoding FIBCD1 maps to human chromosome 9, which contains 145 million base pairs, comprises 4% of the human genome and encodes nearly 900 genes. Function: NAD-dependent lysine demalonylase and desuccinylase that specifically removes malonyl and succinyl groups on target proteins. Activates CPS1 and contributes to the regulation of blood ammonia levels during prolonged fasting: acts by mediating desuccinylation of CPS1, thereby increasing CPS1 activity in response to elevated NAD levels during fasting. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. Can deacetylate cytochrome c (CYCS) and a number of other proteins in vitro. Subunit: Interacts with CPS1 (By similarity). Monomer. Homodimer. Forms homodimers upon suramin binding. Subcellular Location: Mitochondrion matrix. Mitochondrion intermembrane space. Isoform 1: Cytoplasm. Mitochondrion. Isoform 2: Mitochondrion. Tissue Specificity: Widely expressed. Similarity: Belongs to the sirtuin family. Class III subfamily. Contains 1 deacetylase sirtuin-type domain. Database links: Entrez Gene: 84929 Human Entrez Gene: 98970 Mouse Entrez Gene: 311861 Rat SwissProt: Q8N539 Human SwissProt: A2AV25 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
FIbCD1是含有一个纤维蛋白原C-末端结构域的461氨基酸单程膜蛋白，以多个交替剪接的亚型存在。编码FiBCD1的基因编码到人类9号染色体上，包含1亿4500万个碱基对，包含4%的人类基因组，编码近900个基因。