FITC标记的脱氧核糖核酸酶2B抗体
产品名称： FITC标记的脱氧核糖核酸酶2B抗体
英文名称： Anti-DNASE2B/FITC
产品编号： HZ-14396R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-DNASE2B/FITC Conjugated antibody
FITC标记的脱氧核糖核酸酶2B抗体
| 英文名称 | Anti-DNASE2B/FITC |
| 中文名称 | FITC标记的脱氧核糖核酸酶2B抗体 |
| 别 名 | Deoxyribonuclease 2 beta; Deoxyribonuclease 2 beta precursor; Deoxyribonuclease II beta; DLAD; DNase 2 like acid DNase; DNASE 2B; DNase II beta; DNase II like acid DNase; DNASE2; DNase2 like acid DNase; DnaseIIb; DNS2B_HUMAN; EC 3.1.22.1; Endonuclease DLAD; Lysosomal DNase II; UOX. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 神经生物学 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Pig, Horse, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 39kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human DNASE2B |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: The protein encoded by this gene shares considerable sequence similarity to, and is structurally related to DNase II. The latter is a well characterized endonuclease that catalyzes DNA hydrolysis in the absence of divalent cations at acidic pH. Unlike DNase II which is ubiquitously expressed, expression of this gene product is restricted to the salivary gland and lungs. The gene has been localized to chromosome 1p22.3 adjacent (and in opposite orientation) to the uricase pseudogene. Two transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008] Function: DNASE2B shares considerable sequence similarity to, and is structurally related to DNase II. The latter is a well characterized endonuclease that catalyzes DNA hydrolysis in the absence of divalent cations at acidic pH. Unlike DNase II which is ubiquitously expressed, expression of this protein is restricted to the salivary gland and lungs. The gene has been localized to chromosome 1p22.3 adjacent (and in opposite orientation) to the uricase pseudogene. Two transcript variants encoding different isoforms have been described for this gene. Subcellular Location: Lysosome Similarity: Belongs to the DNase II family. Database links: Entrez Gene: 58511 Human Omim: 608057 Human SwissProt: Q8WZ79 Human Unigene: 129142 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
由该基因编码的蛋白质具有相当的序列相似性，并且在结构上与DNA酶II相关。后者是具有良好特性的内切核酸酶，在酸性pH下在没有二价阳离子的情况下催化DNA水解。与普遍表达的DNase II不同，该基因产物的表达仅限于唾液腺和肺。该基因已定位于与尿酸酶假基因相邻的染色体1P2.2.3（和相反的取向）。两个转录变体