FITC标记的组蛋白H1抗体
产品名称: FITC标记的组蛋白H1抗体
英文名称: Anti-Histone H1t/FITC
产品编号: HZ-1413R-FITC
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围:
上海沪震实业有限公司
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Rabbit Anti-Histone H1t/FITC Conjugated antibody
FITC标记的组蛋白H1抗体
英文名称 | Anti-Histone H1t/FITC |
中文名称 | FITC标记的组蛋白H1抗体 |
别 名 | H1 histone family, member T (testis specific); H1FT; H1T; H1T_HUMAN; Hist1h1t; Histone cluster 1, H1t; Testicular H1 histone. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 肿瘤 免疫学 转录调节因子 表观遗传学 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, |
产品应用 | not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 22kDa |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human Testicular H1 histone |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. Function: Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures. Subcellular Location: Nucleus. Chromosome. Post-translational modifications: Phosphorylated in early spermatids. Similarity: Belongs to the histone H1/H5 family. Contains 1 H15 (linker histone H1/H5 globular) domain. Database links: Entrez Gene: 3010 Human Omim: 142712 Human SwissProt: P22492 Human Unigene: 533293 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
组蛋白是真核生物中染色体纤维的核小体结构的基本核蛋白。四个核心组蛋白(H2A、H2B、H3和H4)中的每一个分子形成一个八聚体,其中大约146 bp的DNA被包裹在被称为核小体的重复单元中。连接子组蛋白H1与核小体之间的连接体DNA相互作用,并在染色质的致密化中起到高阶结构的作用。该基因是无内含子的,编码组蛋白H1家族的成员。该基因的转录缺少波利亚尾,而是包含回文终止元件。该基因在6号染色体上的大组蛋白基因簇中发现。