ERBB4抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
ERBB4抗体

ERBB4抗体

商家询价

产品名称: ERBB4抗体

英文名称: ERBB4Antibody

产品编号: XY19943-1

产品价格: null

产品产地: 中国/美国

品牌商标: XYbscience

更新时间: 2023-08-17T09:55:27

使用范围: WB,ELISA,IHC-P,IHC-F,IF

上海信裕生物科技有限公司
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 ERBB4抗体

Applications
In-house applications ELISA, WB, IHC     Application not tested? Please see our Guarantee.
Species specificity Human,Mouse,Rat; other species not tested.
Images
Prev1NextView more validation data
  • 19943-1-AP;mouse brain tissuemouse brain tissue were subjected to SDS PAGE followed by western blot with 19943-1-AP(ERBB4 antibody) at dilution of 1:400
  • 19943-1-AP;human kidney tissueImmunohistochemical of paraffin-embedded human kidney using 19943-1-AP(ERBB4 antibody) at dilution of 1:100 (under 10x lens)
  • 19943-1-AP;human kidney tissueImmunohistochemical of paraffin-embedded human kidney using 19943-1-AP(ERBB4 antibody) at dilution of 1:100 (under 40x lens)
Positive WB detected in Mouse brain tissue
Positive IHC detected in Human kidney tissue
Recommended dilution WB : 1:200-1:1000
IHC : 1:20-1:200
ERBB4抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information
Immunogen Peptide Full name V-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)
Calculated molecular
weight
147 kDa Observed molecular 
weight
147 kDa
GenBank accession 
number
NM_001042599 Gene ID (NCBI) 2066
Gene symbol ERBB4 Synonyms 4ICD, E4ICD, ERBB4, HER4, p180erbB4, s80HER4
BackgroundERBB4抗体

ERBB4, also named as p180erbB4 and HER4, belongs to the protein kinase superfamily, Tyr protein kinase family and EGF receptor subfamily. ERBB4 specifically binds and it is activated by neuregulins, NRG-2, NRG-3, heparin-binding EGF-like growth factor, betacellulin and NTAK. Interaction with these factors induces cell differentiation. ERBB4 is not activated by EGF, TGF-A, and amphiregulin. ERBB4 catalyze the reaction: ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate. The antibody recognize the C-term of ERBB4.ERBB4抗体

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