I型干扰素反应PCR芯片可以检测与干扰素-a和干扰素-β免疫反应相关的基因表达。这款芯片包含了alpha和beta干扰素（IFNs），IFN受体，与干扰素-α、-β反应相关的信号分子，IFN应答基因，与病毒诱导性的以及内源性的干扰素耐受相关的基因。通过实时定量PCR的方法，研究者即能够利用该芯片简单可靠地同时检测干扰素-α，-β反应相关基因的表达。
Interferons & Receptors: IFNA1, IFNA2, IFNA4, IFNAR1, IFNAR2, IFNB1, IFNE, IFNW1. Interferon-Responsive Genes: Innate Immunity: ADAR, BST2, CASP1 (ICE), CCL2 (MCP-1), CCL5 (RANTES), DDX58, GBP1, HLA-E, HLA-G, IFI27, IFI30, IFI6 (G1P3), IFIH1, IFIT1, IFIT2, IFIT3, IFITM1 (9-27), IFITM2, IFITM3, IRF1, IRF2, IRF7, IRF9 (ISGF3G), ISG15 (G1P2), ISG20, JAK2, MX1, MX2, MYD88, NMI, OAS1, OAS2, PML, SOCS1, STAT1, STAT2, TAP1 (ABCB2), TLR3, TLR7. Adaptive Immunity: CD80, CRP, MYD88, TAP1 (ABCB2). Cytokines: CCL2 (MCP-1), CCL5 (RANTES), CXCL10 (INP10), IL15, TNFSF10 (TRAIL). Apoptosis: ADAR, CASP1 (ICE), CCL2 (MCP-1), CCL5 (RANTES), EIF2AK2 (PRKR), IFI16, IFI27, IFI6 (G1P3), IFIH1, JAK2, MX1, MYD88, PML, STAT1, TIMP1, TLR3, TNFSF10 (TRAIL). Other Genes Involved in Type I Interferon Response: Innate Immunity: CD86, CIITA, HLA-A, HLA-B, IFNA2, IFNA4, IFNAR1, IFNAR2, IFNB1, IRF3, IRF5, JAK1, NOS2 (iNOS), SH2D1A, STAT3, TICAM1 (TRIF), TLR8, TLR9, TMEM173, TRAF3, TYK2. Adaptive Immunity: IFNA2, IFNB1, IL10, TLR8, VEGFA. Cytokines: CD70 (TNFSF7), IL10, IL6, VEGFA. Apoptosis: BAG3, CAV1, CD70 (TNFSF7), CDKN1B (p27KIP1), IFNA2, IFNB1, IL10, IL6, MAL, MET, MNDA, PRKCZ, PSME2, SHB, TICAM1 (TRIF), TMEM173, TRAF3, VEGFA