CDX4,尾型同源盒转录因子4抗体

产品编号HZ-12301R
英文名称CDX4
中文名称尾型同源盒转录因子4抗体
别 名Caudal-type homeobox protein 4; CDX4; CDX4_HUMAN; Homeobox protein CDX-4.
说 明 书0.1ml 0.2ml
研究领域细胞生物 干细胞 表观遗传学
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep,
CDX4,尾型同源盒转录因子4抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量30kDa
细胞定位细胞核
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from Human CDX4
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
CDX4,尾型同源盒转录因子4抗体PubMedPubMed
产品介绍background:
Cdx1, Cdx2 and Cdx4 are members of the caudal-type homeobox family of genes, which are homologs of the Drosophila “caudal” gene required for anterior-posterior regional identity. The proteins encoded by these genes are transcription factors which play an important role in development by regulating the expression of Hox genes. Hox genes play a fundamental role in the development of the vertebrate central nervous system, heart, axial skeleton, limbs, gut, urogenital tract and external genitalia. Cdx4 is a major positive regulator of the expression of all Hox family members. Due to its critical role as a regulator, Cdx4 is a direct target of the canonical Wnt pathway. The loss of Cdx4 can result in the development of an expanded hindbrain, while the overexpression of Cdx4 may cause the hindbrain to lose its distinct segmental features and resemble the spinal cord.

Subcellular Location:
Nucleus.

Similarity:
Belongs to the Caudal homeobox family.
Contains 1 homeobox DNA-binding domain.

Database links:
UniProtKB/Swiss-Prot: O14627.1

CDX4,尾型同源盒转录因子4抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.