GEFT 抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
GEFT 抗体

GEFT 抗体

商家询价

产品名称： GEFT 抗体

英文名称： GEFT Antibody

产品编号： XY 17028-1-

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

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 GEFT 抗体

Applications
Tested Applications: ELISA, WB, IP
Specificity Reaction: Human,Mouse,Rat; Other species are not tested.Please decide the specificity by homology
Positive WB detected in Human brain tissue, Transfected HEK-293 cells
Positive IP detected in HEK-293 cells
Recommended dilution WB : 1:200-1:1000
IP : 1:200-1:1000
 GEFT 抗体Application key: WB=Western Blotting ,IHC=Immunohistochemistry, IF=Immunofluorescence
Images
Prev1NextView more validation data
  • 17028-1-AP;human brain tissuehuman brain tissue were subjected to SDS PAGE followed by western blot with 17028-1-AP(GEFT antibody) at dilution of 1:300
  • 17028-1-AP;HEK-293 cellsIP Result of anti-GEFT (IP:17028-1-AP, 4ug; Detection:17028-1-AP 1:400) with HEK-293 cells lysate 2000ug.
  • 17028-1-AP;Transfected HEK-293 cellsTransfected HEK-293 cells were subjected to SDS PAGE followed by western blot with 17028-1-AP( GEFT Antibody) at dilution of 1:1000
Product Information GEFT 抗体
Source: Rabbit Purify: Antigen affinity purification
IsoType: IgG Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3. -20oC, Avoid freeze / thaw cycles.
Immunogen Information
Immunogen: GEFT fusion protein ag10436 Full Name: RhoA/RAC/CDC42 exchange factor
Caculated Molecular
Weight:		 474aa,53 kDa Observed Molecular 
Weight:		 64 kDa
GenbankNo BC012860 GeneID: 115557
Symbol GEFT Synonyms GEFT, p63RhoGEF, RhoA/RAC/CDC42 exchange factor
Background

GEFT, also named as p63RhoGEF, may play a role in actin cytoskeleton reorganization in different tissues since its activation induces formation of actin stress fibers. It works as a guanine nucleotide exchange factor for Rho family of small GTPases. GETF links specifically G alpha q/11-coupled receptors to RHOA activation. GEFT may be an important regulator of processes involved in axon and dendrite formation. In neurons seems to be an exchange factor primarily for RAC1. It is involved in skeletal myogenesis. GEFT 抗体

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