FITC标记的氧固醇结合蛋白1抗体
产品名称： FITC标记的氧固醇结合蛋白1抗体
英文名称： Anti-OSBP1/FITC
产品编号： HZ-17515R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
上海沪震实业有限公司
- 联系人 : 鲍丽雯
- 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
- 邮编 : 200612
- 所在区域 : 上海
- 电话 : 139****0749 点击查看
- 传真 : 点击查看
- 邮箱 : www.shzbio.net
- 二维码 : 点击查看
Rabbit Anti-OSBP1/FITC Conjugated antibody
FITC标记的氧固醇结合蛋白1抗体
| 英文名称 | Anti-OSBP1/FITC |
| 中文名称 | FITC标记的氧固醇结合蛋白1抗体 |
| 别 名 | OSBP 1; OSBP; OSBP1_HUMAN; Oxysterol binding protein 1; Oxysterol-binding protein 1. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 发育生物学 信号转导 新陈代谢 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 89kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human OSBP1 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Oxysterol binding protein is an intracellular protein that is believed to transport sterols from lysosomes to the nucleus where the sterol down-regulates the genes for the LDL receptor, HMG-CoA reductase, and HMG synthetase [provided by RefSeq, Jul 2008] Function: Binds cholesterol and a range of oxysterols. Cholesterol binding promotes the formation of a complex with PP2A and a tyrosine phosphatase which dephosphorylate ERK1/2, whereas 25-hydroxycholesterol causes its disassembly. Regulates cholesterol efflux by decreasing ABCA1 stability. Subunit: Homodimer or homotrimer. Interacts with VAPA. Subcellular Location: Cytoplasm. Golgi apparatus membrane. When bound to oxysterols, translocates to the periphery of Golgi membranes. Tissue Specificity: Widely expressed. Similarity: Belongs to the OSBP family. Contains 1 PH domain. Database links: Entrez Gene: 5007 Human Entrez Gene: 76303 Mouse Entrez Gene: 365410 Rat Omim: 167040 Human SwissProt: P22059 Human SwissProt: Q3B7Z2 Mouse Unigene: 597091 Human Unigene: 291279 Mouse Unigene: 107910 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
羟甾醇结合蛋白是一种胞内蛋白，据信可将甾醇从溶酶体运输到细胞核，在那里甾醇下调LDL受体、HMG-CoA还原酶和HMG合成酶的基因[由RefSeq，2008年7月提供]。