DNAJC14,DNAJC14蛋白抗体

产品编号HZ-14381R
英文名称DNAJC14
中文名称DNAJC14蛋白抗体
别 名DJC14_HUMAN; DnaJ (Hsp40) homolog, subfamily C, member 14; DNAJ; DnaJ homolog subfamily C member 14; DnaJ protein homolog 3; DNAJC14; Dopamine receptor interacting protein; Dopamine receptor-interacting protein of 78 kDa; DRiP78; hDj 3; HDJ-3; HDJ3; Human DnaJ protein 3; LIP6; LYST interacting protein LIP6.
说 明 书0.1ml 0.2ml
研究领域细胞生物 信号转导 转录调节因子 细菌及病毒
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Horse,
DNAJC14,DNAJC14蛋白抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量79kDa
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human DNAJC14
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
DNAJC14,DNAJC14蛋白抗体PubMedPubMed
产品介绍background:
The DnaJ family is one of the largest of all the chaperone families and has evolved with diverse cellular localization and functions. The presence of the J domain defines a protein as a member of the DnaJ family. DnaJ heat shock induced proteins are from the bacterium Escherichia coli and are under the control of the htpR regulatory protein. The DnaJ proteins play a critical role in the HSP 70 chaperone machine by interacting with HSP 70 to stimulate ATP hydrolysis. DnaJ proteins are important mediators of proteolysis and are involved in the regulation of protein degradation, exocytosis and endocytosis. DnaJC14 (DnaJ homolog subfamily C member 14), also known as DRIP78 (Dopamine receptor-interacting protein of 78 kDa) and HDJ3 (Human DnaJ protein 3), is a 702 amino acid endoplasmic reticulular membrane protein that contains one J domain. DnaJC14 regulates the export of target proteins, such as the dopamine D1 receptor (D1DR), from the endoplasmic reticulum to the cell surface.

Function:
Regulates the export of target proteins, such as DRD1, from the endoplasmic reticulum to the cell surface.

Subcellular Location:
Endoplasmic reticulum membrane.

Tissue Specificity:
Highly expressed in pancreas and selectively expressed in brain, lung, liver, skeletal muscle and kidney.

DNAJC14,DNAJC14蛋白抗体Similarity:
Contains 1 J domain.

Gene ID:
85406

Database links:
Entrez Gene: 85406 Human
Entrez Gene: 74330 Mouse
Entrez Gene: 114481 Rat
Omim: 606092 Human
SwissProt: Q6Y2X3 Human
SwissProt: Q921R4 Mouse
SwissProt: Q5XIX0 Rat
Unigene: 709320 Human
Unigene: 296915 Mouse
Unigene: 114340 Rat

DNAJC14,DNAJC14蛋白抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.