FITC标记的TRIM66蛋白抗体
产品名称： FITC标记的TRIM66蛋白抗体
英文名称： Anti-TRIM66/FITC
产品编号： HZ-17121R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-TRIM66/FITC Conjugated antibody
FITC标记的TRIM66蛋白抗体
| 英文名称 | Anti-TRIM66/FITC |
| 中文名称 | FITC标记的TRIM66蛋白抗体 |
| 别 名 | TRI66_HUMAN; Trim66; Tripartite motif-containing protein 66. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 转录调节因子 锌指蛋白 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 135kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human TRIM66 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | Function: May function as transcription repressor; The repressive effects are mediated, at least in part, by recruitment of deacetylase activity. May play a role as negative regulator of postmeiotic genes acting through CBX3 complex formation and centromere association. Subunit: Can form homodimers and heterodimers. Interacts with CBX5, CBX1 and CBX3 via PxVxL motif (By similarity). Subcellular Location: Nucleus. Forms discrete foci within the centromeric chromocenter and surrounding nucleoplasm. Similarity: Contains 2 B box-type zinc fingers. Contains 1 bromo domain. Contains 1 PHD-type zinc finger. Database links: Entrez Gene: 9866 Human Omim: 612000 Human SwissProt: O15016 Human Unigene: 130836 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
可能作为转录抑制因子发挥作用；抑制效应至少部分是通过激活去乙酰化酶活性来介导的。可能是通过CBX3复合物形成和着丝粒结合作用的减数分裂基因的负调控因子。