ZBTB7B 抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
ZBTB7B 抗体

ZBTB7B 抗体

商家询价

产品名称： ZBTB7B 抗体

英文名称： ZBTB7B Antibody

产品编号： XY11341-1

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

上海信裕生物科技有限公司
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 ZBTB7B 抗体Applications

In-house applications ELISA, WB, IF, IP     Application not tested? Please see our Guarantee.
Species specificity Human,Mouse,Rat; other species not tested.
Images
Prev1NextView more validation data
  • 11341-1-AP;human skin tissuehuman skin tissue were subjected to SDS PAGE followed by western blot with 11341-1-AP(ZBTB7B antibody) at dilution of 1:400
  • 11341-1-AP;HelaImmunofluorescent analysis of Hela cells, using ZBTB7B antibody 11341-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
  • 11341-1-AP;mouse skin tissueIP Result of anti-ZBTB7B (IP:11341-1-AP, 4ug; Detection:11341-1-AP 1:300) with mouse skin tissue lysate 3200ug.
Positive WB detected in Human skin tissue
Positive IP detected in Mouse skin tissue
Positive IF detected in Hela cells, MCF-7 cells
Recommended dilution WB : 1:200-1:2000
IP : 1:200-1:1000
IF : 1:10-1:100
 ZBTB7B 抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information
Immunogen ZBTB7B fusion protein ag1888 Full name Zinc finger and BTB domain containing 7B
Calculated molecular
weight		 539aa,58 kDa Observed molecular 
weight		 58kd
GenBank accession 
number		 BC012070 Gene ID (NCBI) 51043
Gene symbol ZBTB7B Synonyms C Krox, DKFZp686G01254, hcKrox, THPOK, ZBTB15, ZBTB7B, Zfp 67, ZFP67, Zinc finger protein 67 homolog, Zinc finger protein Th POK, ZNF857B
Background ZBTB7B 抗体

ZBTB7B belongs to a large family of transcription factors, generally acting as repressors, characterized by a carboxy-terminal DNA binding domain made of multiple zinc fingers (four in Thpok) and an amino-terminal BTB-POZ domain that mediates homo- (and possibly hetero-) dimerization [PMID: 17084908]. Zbtb7b is up-regulated by MHC-II-restricted thymocytes during their CD4 differentiation and is a major determinant of CD4 lineage choice. Two properties of ZBTB7B deserve attention. First, although Thpok is expressed in a wide variety of cells, its expression in the thymus is highly lineage-specific : CD4 SP thymocytes (and all CD4 T cells) express Thpok, whereas DP and CD8 SP thymocytes do notSecond, both loss- and gain-of-function experiments indicate that Thpok affects lineage choice but not positive selection [PMID: 15729333, 10550051]. ZBTB7B 抗体

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