FITC标记的神经细胞膜糖蛋白M6a抗体-抗体-抗体-生物在线
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FITC标记的神经细胞膜糖蛋白M6a抗体

FITC标记的神经细胞膜糖蛋白M6a抗体

商家询价

产品名称: FITC标记的神经细胞膜糖蛋白M6a抗体

英文名称: Anti-GPM6A/FITC

产品编号: HZ-10757R-FITC

产品价格: null

产品产地: 中国/上海

品牌商标: HZbscience

更新时间: 2023-08-17T10:24:20

使用范围: Flow-Cyt=1:50-200 ICC=1:50-200 IF=1:50-200

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 Rabbit Anti-GPM6A/FITC Conjugated antibody

FITC标记的神经细胞膜糖蛋白M6a抗体

 

英文名称 Anti-GPM6A/FITC
中文名称 FITC标记的神经细胞膜糖蛋白M6a抗体
别    名 GPM6A; GPM6A_HUMAN; M6a; M6 a; M6-a; Neuronal membrane glycoprotein M6-a.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  神经生物学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Rabbit, 
产品应用 Flow-Cyt=1:50-200 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 31kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GPM6A
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
GPM6A (Glycoprotein M6A) is a Protein Coding gene. GO annotations related to this gene include calcium channel activity. An important paralog of this gene is GPM6B.

Function:
Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca(2+) influx. May be involved in regulation of endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs); enhances internalization and recycling of mu-type opioid receptor.

Subunit:
Interacts with OPRM1 

Subcellular Location:
Cell membrane; Multi-pass membrane protein. Cell projection, axon. Cell projection, dendritic spine. Cell projection, filopodium. Note=Localizes to cholesterol-rich lipid rafts of the plasma membrane of hippocampal neurons. Localized to plasma membrane of cell bodies and neurites of hippocampal neurons. Localized in membrane protrusions (filopodia and spines) of primary hippocampal neurons. Localized to the growth cone edge membrane of elongating axons.

Similarity:
Belongs to the myelin proteolipid protein family.

Database links:

Entrez Gene: 2823 Human

Entrez Gene: 234267 Mouse

Omim: 601275 Human

SwissProt: P51674 Human

SwissProt: P35802 Mouse

Unigene: 75819 Human

Unigene: 241700 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications
   

GPM6A(糖蛋白M6A)是一种蛋白质编码基因。与此基因相关的注释包括钙通道活性。该基因的一个重要旁系同源基因是GPM6B。