FITC标记的Pellino 1蛋白抗体
产品名称： FITC标记的Pellino 1蛋白抗体
英文名称： Anti-Pellino 1/FITC
产品编号： HZ-12614R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-Pellino 1/FITC Conjugated antibody
FITC标记的Pellino 1蛋白抗体
| 英文名称 | Anti-Pellino 1/FITC |
| 中文名称 | FITC标记的Pellino 1蛋白抗体 |
| 别 名 | E3 ubiquitin-protein ligase pellino homolog 1; PELI1; PELI1_HUMAN; Pellino E3 ubiquitin protein ligase 1; Pellino homolog 1; Pellino protein; Pellino-1; Pellino-related intracellular-signaling molecule; Pellino1; PRISM; Protein pellino homolog 1. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 信号转导 激酶和磷酸酶 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 46kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Pellino 1 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | Function: Scaffold protein involved in the IL-1 signaling pathway via its interaction with the complex containing IRAK kinases and TRAF6. Required for NF-kappa-B activation and IL-8 gene expression in response to IL-1. Post-translational modifications: Phosphorylation by IRAK1 and IRAK4 enhances its E3 ligase activity. Similarity: Belongs to the pellino family. Database links: Entrez Gene: 421279 Chicken Entrez Gene: 535054 Cow Entrez Gene: 57162 Human Entrez Gene: 67245 Mouse Entrez Gene: 305549 Rat Entrez Gene: 558420 Zebrafish Omim: 614797 Human SwissProt: Q96FA3 Human SwissProt: Q8C669 Mouse Unigene: 727530 Human Unigene: 28957 Mouse Unigene: 22814 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
支架蛋白通过与含有IRAK激酶和TRAF6的复合物相互作用参与IL-1信号通路。IL-1对NF-κB活化和IL-8基因表达的影响