FITC标记的细胞质多聚腺苷酸结合蛋白3抗体
产品名称： FITC标记的细胞质多聚腺苷酸结合蛋白3抗体
英文名称： Anti-CPEB3/FITC
产品编号： HZ-11340R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-CPEB3/FITC Conjugated antibody
FITC标记的细胞质多聚腺苷酸结合蛋白3抗体
| 产品编号 | bs-11340R-FITC |
| 英文名称 | Anti-CPEB3/FITC |
| 中文名称 | FITC标记的细胞质多聚腺苷酸结合蛋白3抗体 |
| 别 名 | CPE-binding protein 3; CPE-BP3; CPEB 3; Cpeb3; CPEB3_HUMAN; Cytoplasmic polyadenylation element binding protein 3; Cytoplasmic polyadenylation element-binding protein 3; hCPEB-3; KIAA0940. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 神经生物学 细胞周期蛋白 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 76kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human CPEB3 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: The regulated translation of messenger RNA is essential for cell-cycle progression, establishment of the body plan during early development and modulation of key activities in the central nervous system. Cytoplasmic polyadenylation, one mechanism of controlling translation, is driven by cytoplasmic polyadenylation element binding proteins, called CPEBs. CPEB3 (cytoplasmic polyadenylation element binding protein 3) is a 698 amino acid protein that contains two RNA recognition motif (RRM) domains and, like other CPEB proteins, may play a role in the maturation of the central nervous system. CPEB3 exists as multiple alternatively spliced isoforms that are encoded by a gene which maps to human chromosome 10, which houses over 1,200 genes and comprises nearly 4.5% of the human genome. Similarity: Belongs to the RRM CPEB family. Contains 2 RRM (RNA recognition motif) domains. Database links: Entrez Gene: 22849 Human Entrez Gene: 208922 Mouse SwissProt: Q8NE35 Human SwissProt: Q7TN99 Mouse Unigene: 131683 Human Unigene: 701732 Human Unigene: 371677 Mouse Unigene: 391176 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
信使RNA的调节翻译对于细胞周期的发展、在早期发育中建立身体计划和调节中枢神经系统的关键活动是必不可少的。细胞质多聚腺苷酸化是控制翻译的一种机制，是由细胞质聚腺苷酸化元件结合蛋白驱动的，称为cPEBS。CPEB3（细胞质聚腺苷酸化元件结合蛋白3）是包含两个RNA识别基序（RRM）结构域的698个氨基酸蛋白，与其他cPEB蛋白一样，可能在中枢神经系统的成熟中起作用。CPEB3以多个交替剪接的亚型存在，该亚型由一个基因编码，该基因映射到人类10号染色体，该基因含有1200个以上的基因，并包含人类基因组的近4.5%。