FITC标记的肌动蛋白相关蛋白2/3亚型1A抗体
产品名称: FITC标记的肌动蛋白相关蛋白2/3亚型1A抗体
英文名称: Anti-ARPC1A/FITC
产品编号: HZ-12526R-FITC
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: ICC=1:50-200 IF=1:50-200
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Rabbit Anti-ARPC1A/FITC Conjugated antibody
FITC标记的肌动蛋白相关蛋白2/3亚型1A抗体
英文名称 | Anti-ARPC1A/FITC |
中文名称 | FITC标记的肌动蛋白相关蛋白2/3亚型1A抗体 |
别 名 | Actin binding protein (Schizosaccharomyces pombe sop2 like); Actin related protein 2/3 complex subunit 1A 41kDa; Actin-related protein 2/3 complex subunit 1A; ARC1A_HUMAN; Arc40; ARPC1A; SOP2-like protein; SOP2Hs; SOP2L. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 细胞生物 信号转导 细胞骨架 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit, Sheep, |
产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 42kDa |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human ARPC1A |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: This gene encodes one of seven subunits of the human Arp2/3 protein complex. This subunit is a member of the SOP2 family of proteins and is most similar to the protein encoded by gene ARPC1B. The similarity between these two proteins suggests that they both may function as p41 subunit of the human Arp2/3 complex that has been implicated in the control of actin polymerization in cells. It is possible that the p41 subunit is involved in assembling and maintaining the structure of the Arp2/3 complex. Multiple versions of the p41 subunit may adapt the functions of the complex to different cell types or developmental stages. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010]. Function: Probably functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Subunit: Probable component of the Arp2/3 complex in which it may replace ARPC1B. Subcellular Location: Cytoplasm; cytoskeleton. Similarity: Belongs to the WD repeat ARPC1 family. Contains 6 WD repeats. Database links: UniProtKB/Swiss-Prot: Q92747.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
该基因编码人类ARP2/3蛋白复合物的七个亚基之一。这个亚基是SOP2蛋白家族的成员,并且与ARPC1B基因编码的蛋白非常相似。这两种蛋白之间的相似性表明它们都可能作为人Arp2/3复合物的p41亚基起作用,这与肌动蛋白聚合的控制有关。细胞中的N。P41亚基参与组装和维持ARP2/3复合物的结构是可能的。P41亚基的多个版本可以适应复杂的功能到不同的细胞类型或发育阶段。另一种编码不同的异构体的剪接转录变体已被发现用于该基因。[ RefSeq,JUL 2010 ]提供。