DOM3Z,DOM3Z蛋白抗体

产品编号HZ-9054R
英文名称DOM3Z
中文名称DOM3Z蛋白抗体
别 名Dom 3 homolog Z; DOM 3Z; Dom-3 homolog Z; DOM3 C. elegans homolog of Z; Dom3 homolog Z; DOM3L; Dom3z; DOM3Z_HUMAN; NG6; Protein Dom3Z.
说 明 书0.1ml 0.2ml
研究领域细胞生物 免疫学
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Pig, Cow, Rabbit, Sheep,
DOM3Z,DOM3Z蛋白抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量45kDa
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human DOM3Z
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
DOM3Z,DOM3Z蛋白抗体PubMedPubMed
产品介绍background:
DOM3Z, also known as NG6 or DOM3L, is a 396 amino acid ubiquitously expressed protein belonging to the Dom3Z family. The gene encoding DOM3Z maps to human chromosome 6 in the major histocompatibility complex (MHC) class III region. Chromosome 6 contains 170 million base pairs and comprises nearly 6% of the human genome. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Additionally, Porphyria cutanea tarda, Parkinson's disease and Stickler syndrome are all associated with genes that map to chromosome 6.

Function:
May possess pyrophosphohydrolase activity towards 5' triphosphorylated RNA (By similarity).

Tissue Specificity:
Ubiquitously expressed

Similarity:
Belongs to the Dom3Z family.

Database links:
Entrez Gene: 508460 Cow
Entrez Gene: 1797 Human
Entrez Gene: 112403 Mouse
Entrez Gene: 100124385 Pig
Entrez Gene: 361799 Rat
Omim: 605996 Human
SwissProt: Q5E9Y5 Cow
SwissProt: O77932 Human
SwissProt: O70348 Mouse
SwissProt: Q6MG77 Rat
Unigene: 153299 Human
Unigene: 275309 Mouse
Unigene: 20463 Rat

DOM3Z,DOM3Z蛋白抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.