PeproTech大鼠抗小鼠CD18 SAFIRE (Functional)
产品名称： PeproTech大鼠抗小鼠CD18 SAFIRE (Functional)
英文名称： Anti-Mouse CD18 SAFIRE Purified
产品编号： 10212-25-100
产品价格： null
产品产地： USA
品牌商标： peperotech(BioGems)
更新时间： null
使用范围： 功能性，流式
美国PeproTech(派普泰克)公司中国代表处
- 联系人 :
- 地址 :  江苏省苏州市工业园区星湖街218号A1北座4楼L03
- 邮编 : 215123
- 所在区域 : 江苏
- 电话 : 点击查看
- 传真 : 点击查看
- 邮箱 : peprotech.infochina@thermofisher.com
The M18/2 monoclonal antibody specifically binds to mouse CD18, a 95kDA integrin beta 2 glycoprotein. CD18 is expressed on all leukocytes with the highest density by NK and T cells. CD18 forms LFA-1 with CD11a, Mac-1 with CD11b and gp150/95 with CD11c. Through these interactions, CD18 has an important role in cellular adhesion. The M18/2 antibody is reported to stimulate Mac-1 and LFA-1 adhesion to their ligands and block tumor cell metastasis.