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上海信裕生物科技有限公司
AVEN抗体

AVEN抗体

商家询价

产品名称： AVEN抗体

英文名称： AVENAntibody

产品编号： XY25846-1

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

上海信裕生物科技有限公司
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 AVEN抗体

Applications
In-house applications ELISA, WB     Application not tested? Please see our Guarantee.
Species specificity Human; other species not tested.
Images
Prev1NextView more validation data
  • 25846-1-AP;MCF-7 cellsMCF-7 cells were subjected to SDS PAGE followed by western blot with 25846-1-AP( AVEN Antibody) at dilution of 1:1000
Positive WB detected in MCF-7 cells, K-562 cells
Recommended dilution WB : 1:500-1:5000
 AVEN抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information
Immunogen AVEN fusion protein Ag23020 Full name Apoptosis, caspase activation inhibitor
Calculated molecular
weight		 39 kDa Observed molecular 
weight		 50 kDa
GenBank accession 
number		 BC010488 Gene ID (NCBI) 57099
Gene symbol AVEN Synonyms AVEN, Cell death regulator Aven, PDCD12
Background AVEN抗体

AVEN (Apoptosis caspase activation inhibitor) is known to play a role in male and female germ cell development. AVEN protein has also been shown to inhibit the mitochondrial apoptosis pathway by binding to and inhibiting the self-association of proapoptotic APAF-1, as well as binding to and enhancing antiapoptotic BCL-xL activity. AVEN has also recently been shown to function as an activator of the cell cycle-regulating ATM kinase in the DNA damage response pathway. Molecular weight of this protein detected by WB is 50 kDa (PMID: 22751129). AVEN抗体

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