ENO1+ENO2+ENO3,神经元，肌肉特异性烯醇化酶抗体

产品编号HZ-6273R
英文名称ENO1+ENO2+ENO3
中文名称神经元，肌肉特异性烯醇化酶抗体
别 名ENO1 + ENO2 + ENO3; 2-phospho-D-glycerate hydro-lyase; Alpha-enolase; Beta-enolase; C-myc promoter-binding protein; Crystallin Tau, included; ENO1L1; Enolase 1, (alpha); Enolase 2 (gamma, neuronal); Enolase 2; Enolase 3 (beta, muscle); Enolase 3; Enolase alpha; Enolase, beta; Enolase, gamma; Enolase, muscle specific; Enolase, neuron specific; Enolase, nonneuronal, included; Gamma-enolase; GSD13; MBP-1; MPB1; MSE; Muscle-specific enolase; Neural enolase; Neuron-specific enolase; NNE; Non-neural enolase; NSE; Phosphpyruvate hydratase; Plasminogen-binding protein; Skeletal muscle enolase.
说 明 书0.1ml 0.2ml
研究领域肿瘤 细胞生物 染色质和核信号 信号转导 转录调节因子 激酶和磷酸酶 肿瘤细胞生物标志物 新陈代谢 表观遗传学
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Pig, Cow, Horse,
ENO1+ENO2+ENO3,神经元，肌肉特异性烯醇化酶抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量48kDa
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human ENO1+ENO2+ENO3
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
ENO1+ENO2+ENO3,神经元，肌肉特异性烯醇化酶抗体PubMedPubMed
产品介绍background:
Enolase 1 is a multifunctional enzyme that, as well as its role in glycolysis, plays a part in various processes such as growth control, hypoxia tolerance and allergic responses. May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons. Stimulates immunoglobulin production. MBP1 binds to the myc promoter and acts as a transcriptional repressor. May be a tumor suppressor.
Enolase 2 has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium-dependent manner, to cultured neocortical neurons and promotes cell survival.
Enolase 3 appears to have a function in striated muscle development and regeneration.

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

ENO1+ENO2+ENO3,神经元，肌肉特异性烯醇化酶抗体This gene encodes alpha-enolase, one of three enolase isoenzymes found in mammals. Each isoenzyme is a homodimer composed of 2 alpha, 2 gamma, or 2 beta subunits, and functions as a glycolytic enzyme. Alpha-enolase in addition, functions as a structural lens protein (tau-crystallin) in the monomeric form. Alternative splicing of this gene results in a shorter isoform that has been shown to bind to the c-myc promoter and function as a tumor suppressor. Several pseudogenes have been identified, including one on the long arm of chromosome 1. Alpha-enolase has also been identified as an autoantigen in Hashimoto encephalopathy. [provided by RefSeq, Jan 2011].