FITC标记的ITPRIPL1蛋白抗体
产品名称： FITC标记的ITPRIPL1蛋白抗体
英文名称： Anti-ITPRIPL1/FITC
产品编号： HZ-17187R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-ITPRIPL1/FITC Conjugated antibody
FITC标记的ITPRIPL1蛋白抗体
| 英文名称 | Anti-ITPRIPL1/FITC |
| 中文名称 | FITC标记的ITPRIPL1蛋白抗体 |
| 别 名 | Inositol 1,4,5 triphosphate receptor interacting protein like 1; IPIL1; KIAA1754 like; KIAA1754L. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 免疫学 通道蛋白 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Cow, Horse, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 61kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ITPRIPL1 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 癈. |
| 产品介绍 | background: ITPRIPL1 is a 555 amino acid protein belonging to the ITPRIP family. ITPRIPL1 is a single-pass type I membrane protein expressed as two isoforms produced by alternative splicing events. The gene that encodes ITPRIPL1 maps to human chromosome 2, the second largest human chromosome, consisting of 237 million bases encoding over 1,400 genes and making up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstr鰉 syndrome is due to mutations in the ALMS1 gene. It has been hypothesized that human chromosome 2 is the result of an ancient fusion of two ancestral chromosome due to its composition of a vestigial second centromere and vestigial telomeres. Function: The function remains unknown. There are two named isoforms. Subcellular Location: Membrane; Single-pass type I membrane protein Similarity: Belongs to the ITPRIP family. Database links: Entrez Gene: 150771 Human Entrez Gene: 73338 Mouse Entrez Gene: 499885 Rat SwissProt: Q6GPH6 Human SwissProt: A2ASA8 Mouse SwissProt: Q66H52 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
ITPIPR1是属于ITPRIP家族的555个氨基酸。ITPIPPL1是通过交替剪接事件产生的两种异构体表达的单通道I型膜蛋白。编码ITPPL1的基因映射到人类第2号染色体，第二个最大的人类染色体，由2亿3700万个编码超过1400个基因的碱基组成，约占人类基因组的8%。许多遗传疾病与2号染色体上的基因有关。丑角鳞癣，一种罕见的病态皮肤畸形，与ABCA12基因突变有关。脂类代谢紊乱是与ABCG5和ABCG8相关的。ALSTR综合征是一种极为罕见的隐性遗传性疾病，其原因在于ALMS1基因的突变。据推测，人类第2号染色体是由于其第二着丝粒和残留端粒组成的两个祖先染色体的古老融合的结果。