Anti-Proteinase-activated receptor 4/PAR4/FITC Conjugated抗体-抗体-抗体-生物在线
上海沪震实业有限公司
Anti-Proteinase-activated receptor 4/PAR4/FITC Conjugated抗体

Anti-Proteinase-activated receptor 4/PAR4/FITC Conjugated抗体

商家询价

产品名称: Anti-Proteinase-activated receptor 4/PAR4/FITC Conjugated抗体

英文名称: Anti-Proteinase-activated receptor 4/PAR4/FITC

产品编号: YB--9511R-FITC

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:24:20

使用范围: 科研使用

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 Anti-Proteinase-activated receptor 4/PAR4/FITC Conjugated抗体

产品编号 YB-9511R-FITC
英文名称 Anti-Proteinase-activated receptor 4/PAR4/FITC
中文名称 FITC标记的蛋白酶激活受体4抗体
别    名 F2RL3; F2R Like Thrombin/Trypsin Receptor 3; Coagulation Factor II (Thrombin) Receptor-Like 3; Thrombin Receptor-Like 3; PAR-4; PAR4; Coagulation Factor II Receptor-Like 3; Proteinase-Activated Receptor-4; Proteinase-Activated Receptor 4; Protease-Activated Receptor-4; PAR4_HUMAN;   
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 心血管  细胞生物  信号转导  G蛋白偶联受体  G蛋白信号  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 41kDa
细胞定位 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Proteinase-activated receptor 4
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Coagulation factor II (thrombin) receptor-like 3 (F2RL3) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL3 is also a member of the protease-activated receptor family. F2RL3 is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. F2RL3 is activated by thrombin and trypsin. [provided by RefSeq, Jul 2008]

Function:
Receptor for activated thrombin or trypsin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation. 

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Tissue Specificity:
Widely expressed, with highest levels in lung, pancreas, thyroid, testis and small intestine. Not expressed in brain, kidney, spinal cord and peripheral blood leukocytes. Also detected in platelets.

Post-translational modifications:
A proteolytic cleavage generates a new N-terminus that functions as a tethered ligand.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

Database links:

 

Entrez Gene: 9002 Human

Omim: 602779 Human

SwissProt: Q96RI0 Human

Unigene: 137574 Human

 

 



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic application