FBLIM1 monoclonal antibody (M10), clone 5E11
产品名称： FBLIM1 monoclonal antibody (M10), clone 5E11
英文名称： FBLIM1 monoclonal antibody (M10), clone 5E11
产品编号： H00054751-M10
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a partial recombinant FBLIM1.
- Immunogen:
- FBLIM1 (NP_060026, 270 a.a. ~ 373 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- VTCARCIGDESFALGSQNEVYCLDDFYRKFAPVCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILLSVEPTDQGCYPLNNHLFCKPCHVKRSAAGCC
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgG2a Kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.18 KDa) .
- MSDS:
Download
- Publication Reference
- 1.
- Kindlin-1 Is Required for RhoGTPase-Mediated Lamellipodia Formation in Keratinocytes.
Has C, Herz C, Zimina E, Qu HY, He Y, Zhang ZG, Wen TT, Gache Y, Aumailley M, Bruckner-Tuderman L.Am J Pathol. 2009 Oct;175(4):1442-52. Epub 2009 Sep 17.
- Applications
- Western Blot (Cell lysate)
- FBLIM1 monoclonal antibody (M10), clone 5E11 Western Blot analysis of FBLIM1 expression in HepG2 ( Cat # L019V1 ).
- Protocol Download
- Western Blot (Transfected lysate)
- Western Blot analysis of FBLIM1 expression in transfected 293T cell line by FBLIM1 monoclonal antibody (M10), clone 5E11.
Lane 1: FBLIM1 transfected lysate(41 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Western Blot (Recombinant protein)
- Protocol Download
- Sandwich ELISA (Recombinant protein)
- Detection limit for recombinant GST tagged FBLIM1 is approximately 0.03ng/ml as a capture antibody.
- Protocol Download
- Entrez GeneID:
- 54751
- GeneBank Accession#:
- NM_017556
- Protein Accession#:
- NP_060026
- Gene Name:
- FBLIM1
- Gene Alias:
- CAL,DKFZp434G171,FBLP-1,FBLP1,RP11-169K16.5
- Gene Description:
- filamin binding LIM protein 1
- Omim ID:
- 607747
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a protein with an N-terminal filamin-binding domain, a central proline-rich domain, and, multiple C-terminal LIM domains. This protein localizes at cell junctions and may link cell adhesion structures to the actin cytoskeleton. This protein may be involved in the assembly and stabilization of actin-filaments and likely plays a role in modulating cell adhesion, cell morphology and cell motility. This protein also localizes to the nucleus and may affect cardiomyocyte differentiation after binding with the CSX/NKX2-5 transcription factor. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq
- Other Designations:
- CSX-associated LIM,MIG2-interacting protein,OTTHUMP00000003118,OTTHUMP00000003119,OTTHUMP00000003120,filamin-binding LIM protein-1,migfilin,mitogen-inducible 2 interacting protein