FITC标记的脂滴包被蛋白抗体
产品名称： FITC标记的脂滴包被蛋白抗体
英文名称： Anti-Perilipin-2/FITC
产品编号： HZ-10780R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-Perilipin-2/FITC Conjugated antibody
FITC标记的脂滴包被蛋白抗体
| 英文名称 | Anti-Perilipin-2/FITC |
| 中文名称 | FITC标记的脂滴包被蛋白抗体 |
| 别 名 | ADFP; Adipophilin; Adipose differentiation related protein; Adipose differentiation-related protein; ADRP; MGC10598; Perilipin-2; PLIN2; PLIN2_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 心血管 信号转导 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 48kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Perilipin-2 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: The protein encoded by this gene belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material, and maybe involved in development and maintenance of adipose tissue. However, it is not restricted to adipocytes as previously thought, but is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells, and tissues, such as lactating mammary gland, adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis, suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2011] Function: May be involved in development and maintenance of adipose tissue. Subcellular Location: Membrane; Peripheral membrane protein. Tissue Specificity: Milk lipid globules. Post-translational modifications: Acylated; primarily with C14, C16 and C18 fatty acids. Similarity: Belongs to the perilipin family. Database links: Entrez Gene: 123 Human Entrez Gene: 11520 Mouse Omim: 103195 Human SwissProt: Q99541 Human SwissProt: P43883 Mouse SwissProt: Q4PLW0 Pig Unigene: 3416 Human Unigene: 381 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
该基因编码的蛋白属于PyiLIPP家族，其成员涂布胞内脂质储存液滴。该蛋白与脂球表面膜材料有关，可能参与脂肪组织的发育和维持。然而，它并不局限于脂肪细胞，而是广泛存在于培养的细胞系中，包括成纤维细胞、内皮细胞和上皮细胞，以及组织，如乳腺、肾上腺皮质、Sertoli和Leydig细胞，以及酒精性肝中的肝细胞。肝硬化，提示它可以作为多种细胞类型和疾病中脂质积累的标志物。另一种剪接转录变体已经发现这个基因。〔RefSeq，2011〕