FITC标记的白细胞介素23P19抗体
产品名称： FITC标记的白细胞介素23P19抗体
英文名称： Anti-IL23 P19/FITC
产品编号： HZ-18146R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-IL23 P19/FITC Conjugated antibody
FITC标记的白细胞介素23P19抗体
| 英文名称 | Anti-IL23 P19/FITC |
| 中文名称 | FITC标记的白细胞介素23P19抗体 |
| 别 名 | alpha subunit P19; IL-23 subunit alpha; IL-23-A; IL-23p19; IL23; IL23 P 19; IL23A; IL23A_HUMAN; IL23P19; interleukin 23 alpha subunit p19; interleukin 23 P19 subunit; Interleukin-23 subunit alpha; Interleukin-23 subunit p19; JKA3 induced upon T cell activation; MGC79388; P19; SGRF. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 免疫学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 19kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human IL23 P19 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: This gene encodes a subunit of the heterodimeric cytokine interleukin 23 (IL23). IL23 is composed of this protein and the p40 subunit of interleukin 12 (IL12B). The receptor of IL23 is formed by the beta 1 subunit of IL12 (IL12RB1) and an IL23 specific subunit, IL23R. Both IL23 and IL12 can activate the transcription activator STAT4, and stimulate the production of interferon-gamma (IFNG). In contrast to IL12, which acts mainly on naive CD4(+) T cells, IL23 preferentially acts on memory CD4(+) T cells. [provided by RefSeq, Jul 2008] Function: Associates with IL12B to form the IL-23 interleukin, an heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to an heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis. Subcellular Location: Secreted. Secreted upon association with IL12B. Tissue Specificity: Secreted by activated dendritic and phagocytic cells and keratinocytes. Also expressed by dermal Langerhans cells (at protein level). Similarity: Belongs to the IL-6 superfamily. Database links: Entrez Gene: 51561 Human Entrez Gene: 83430 Mouse Entrez Gene: 155140 Rat Omim: 605580 Human SwissProt: Q9NPF7 Human SwissProt: Q9EQ14 Mouse SwissProt: Q91Z84 Rat Unigene: 382212 Human Unigene: 98309 Human Unigene: 125482 Mouse Unigene: 81073 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
This gene encodes a Suunit of the Experdiorly Cytoine Interleuking 23（IL23）.Il23 is composed of this蛋白质and the P40 Suunit of Interleugend 12（IL12B）.The interd of il23 is formed by the beta 1 suunit of il12（Il12RB1）and an il23 specific suunit，il23r . Both Il23 and Il12 can启用the稿Res.Active Active Stat4，and Stimuate the Production of Interferon-Gamma（IFNG）.In Contrst to Il12，which acts mainly on naive CD4（+）t cells，il23 prendally acts on memory CD4（+）t cells .[ provided by Refseq，JUL 2008 ]