COX8C,细胞色素C氧化酶蛋白8C抗体

产品编号HZ-14017R
英文名称COX8C
中文名称细胞色素C氧化酶蛋白8C抗体
别 名COX VIII-3; COX8-3; Cox8c; COX8C_HUMAN; cytochrome c oxidase polypeptide 8; Cytochrome c oxidase polypeptide 8 isoform 3; cytochrome c oxidase polypeptide VIII; Cytochrome c oxidase polypeptide VIII isoform 3; Cytochrome c oxidase subunit 8-3; Cytochrome c oxidase subunit 8C; Cytochrome c oxidase subunit 8C, mitochondrial; cytochrome c oxidase subunit VIII; cytochrome c oxidase subunit VIIIC; mitochondrial.
说 明 书0.1ml 0.2ml
研究领域细胞生物 新陈代谢 线粒体
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human,
COX8C,细胞色素C氧化酶蛋白8C抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量4.8kDa
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human COX8C
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
COX8C,细胞色素C氧化酶蛋白8C抗体PubMedPubMed
产品介绍background:
The cytochrome c oxidase (COX) family of proteins function as the final electron donor in the respiratory chain to drive a proton gradient across the inner mitochondrial membrane, ultimately resulting in the production of water and ATP. The mammalian COX apoenzyme is a dimer, with each monomer consisting of 13 subunits, some of which are mitochondrial and some of which are nuclear. The COX8 (cytochrome c oxidase subunit VIII) subunits are nuclear and have muscle and non-muscle-specific isoforms. COX8 exists as three isoforms: COX8a, a liver and heart isoform, Cox8b, a heart-specific isoform, and Cox8c, whose expression pattern has yet to be elucidated. All three Cox8 isoforms exists as components of the COX complex and play an important role in electron transport.

Function:
This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.

Subcellular Location:
Mitochondrion inner membrane.

Tissue Specificity:
It is not yet known where COX8C is expressed.

Similarity:
Belongs to the cytochrome c oxidase VIII family.

Gene ID:
341947

Database links:
Entrez Gene: 341947 Human
Entrez Gene: 75483 Mouse
Entrez Gene: 360229 Rat
SwissProt: Q7Z4L0 Human
SwissProt: A6H666 Mouse
SwissProt: Q7TNN2 Rat
Unigene: 666459 Human
Unigene: 660 Mouse
Unigene: 98192 Rat

COX8C,细胞色素C氧化酶蛋白8C抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.