糖基化PCR芯片可用于研究编码关键酶的84个基因的表达，这些酶在翻译后，自蛋白多糖和糖蛋白添加和移除糖残基。对蛋白多糖和糖蛋白功能必不可少的成熟的N-连接和O-连接糖链的产生和改变，不仅需要从头寡糖合成的糖基转移酶的活性，也需要重塑所需的糖苷酶和糖基转移酶的活性。无论是通过刺激细胞分化或增生，还是外源性过度表达，导致细胞表面和分泌蛋白的表达增加，需要更多的糖基转移酶和糖苷酶的活性，并且至少部分由其自身的基因表达上升造成的。芯片包含几个重要的糖基转移酶和糖苷酶基因，包括半乳糖，葡萄糖，甘露糖，N-乙酰葡糖胺，N-乙酰基半乳糖胺，岩藻糖和唾液酸。其中一些代表性的酶同时作用于鞘糖脂。使用这一芯片试剂盒及配套试剂检测RNA实验标本，研究者可以简单准确的检测和分析蛋白糖基化相关的基因表达。
N-acetylgalactosaminyltransferases: GALNT1, GALNT10, GALNT11, GALNT12, GALNT13, GALNT14, GALNT2, GALNT3, GALNT4, GALNT6, GALNT7, GALNT8, GALNT9, GALNTL1, GALNTL5, GALNTL6. N-acetylglucosaminyltransferases: A4GNT, B3GNT2, B3GNT3, B3GNT4, B3GNT8, GCNT1, GCNT3, GCNT4, MGAT1, MGAT2, MGAT3, MGAT4A, MGAT4B, MGAT4C, MGAT5, MGAT5B, OGT, POMGNT1. Galactosyltransferases: B3GALTL, B4GALT1, B4GALT2, B4GALT3, B4GALT5, C1GALT1. Glucosyltransferases: UGGT1, UGGT2. Mannosidases: EDEM1, EDEM2, EDEM3, MAN1A1, MAN1A2, MAN1B1, MAN1C1, MAN2A1, MAN2A2, MAN2B1, MANBA. Mannosyltransferases: POMT1, POMT2. Galactosides & Glucosidases & Hexosaminidases: GANAB, GLB1, HEXA, HEXB, MOGS, PRKCSH. Fucosidases & Fucosyltransferases: FUCA1, FUCA2, FUT11, FUT8, POFUT1, POFUT2. Sialidases: NEU1, NEU2, NEU3, NEU4. Sialyltransferases: ST3GAL1, ST3GAL2, ST6GAL1, ST6GALNAC1, ST8SIA2, ST8SIA3, ST8SIA4, ST8SIA6. Mannose-6-Phosphate Synthesis & Catabolism: GNPTAB, GNPTG, NAGPA. Others: AGA, C1GALT1C1. N-Linked Glycosylation: AGA, B3GNT2, B3GNT3, B3GNT8, B4GALT1, B4GALT2, B4GALT3, EDEM1, EDEM2, EDEM3, FUCA1, FUCA2, FUT11, FUT8, GANAB, GLB1, GNPTAB, GNPTG, HEXA, HEXB, MAN1A1, MAN1A2, MAN1B1, MAN1C1, MAN2A1, MAN2A2, MAN2B1, MANBA, MGAT1, MGAT2, MGAT3, MGAT4A, MGAT4B, MGAT4C, MGAT5, MGAT5B, MOGS, NAGPA, NEU1, NEU2, NEU3, NEU4, PRKCSH, ST6GAL1, ST8SIA2, ST8SIA3, ST8SIA4, ST8SIA6, UGGT1, UGGT2. O-Linked Glycosylation: A4GNT, B3GALTL, B3GNT8, B4GALT5, C1GALT1, C1GALT1C1, GALNT1, GALNT10, GALNT11, GALNT12, GALNT13, GALNT14, GALNT2, GALNT3, GALNT4, GALNT6, GALNT7, GALNT8, GALNT9, GALNTL1, GALNTL5, GALNTL6, GCNT1, GCNT3, GCNT4, OGT, POFUT1, POFUT2, POMGNT1, POMT1, POMT2, ST3GAL1, ST3GAL2, ST6GALNAC1, ST8SIA3, ST8SIA6. Glycosphingolipids: B3GNT3, B3GNT4, B4GALT1, B4GALT2, B4GALT3, GLB1, HEXA, HEXB, ST3GAL1, ST3GAL2, ST8SIA6