FITC标记的热休克蛋白70蛋白12A抗体
产品名称： FITC标记的热休克蛋白70蛋白12A抗体
英文名称： Anti-HSPA12A/FITC
产品编号： HZ-18076R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
上海沪震实业有限公司
- 联系人 : 鲍丽雯
- 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
- 邮编 : 200612
- 所在区域 : 上海
- 电话 : 139****0749 点击查看
- 传真 : 点击查看
- 邮箱 : www.shzbio.net
- 二维码 : 点击查看
Rabbit Anti-HSPA12A/FITC Conjugated antibody
FITC标记的热休克蛋白70蛋白12A抗体
| 英文名称 | Anti-HSPA12A/FITC |
| 中文名称 | FITC标记的热休克蛋白70蛋白12A抗体 |
| 别 名 | FLJ13874; Heat shock 70 kDa protein 12A; heat shock 70kD protein 12A; heat shock 70kDa protein 12A; HS12A_HUMAN; Hspa12a; KIAA0417. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 信号转导 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 75kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human HSPA12A |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: The heat shock proteins (HSPs) comprise a group of highly conserved, abundantly expressed proteins with diverse functions, including the assembly and sequestering of multi-protein complexes, the transportation of nascent polypeptide chains across cellular membranes and the regulation of protein folding. HSPA12A (heat shock 70kDa protein 12A) is a 675 amino acid protein that belongs to the HSP 70 family and is expressed in muscle, kidney and brain where it may play a role in cellular metabolism and regulation of neuronal function. The gene encoding HSPA12A maps to human chromosome 10, which houses over 1,200 genes and comprises nearly 4.5% of the human genome. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman’s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria. Tissue Specificity: Widely expressed with highest levels in brain, kidney and muscle. Similarity: Belongs to the heat shock protein 70 family. Database links: Entrez Gene: 259217 Human Entrez Gene: 73442 Mouse Omim: 610701 Human SwissProt: O43301 Human SwissProt: Q8K0U4 Mouse Unigene: 648448 Human Unigene: 39739 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
热休克蛋白（HSP）是一组高度保守的蛋白质，具有不同的功能，丰富的表达，包括装配和封存的多蛋白复合物，新生多肽链跨细胞膜和蛋白质跟监管运输丁。HSPA12A（热休克蛋白12A）是一个675个氨基酸的蛋白质，属于热休克蛋白70家族和表达在肌肉、肾脏和脑的地方可能在细胞的代谢和神经功能的调节作用。编码HSPA12A映射到人类10号染色体上的基因，其中超过1200个基因，包括近4.5%的人类基因组。在某些基因缺陷，映射到10号染色体与Charcot Marie的牙齿疾病有关，杰克逊Weiss综合征、阿瑟小子综合征、nonsyndromatic耳聋，沃尔曼氏综合征，Cowden综合征、多发性内分泌腺瘤2型和卟啉症。