Anti-alpha 2 Macroglobulin/FITC Conjugated抗体
产品名称： Anti-alpha 2 Macroglobulin/FITC Conjugated抗体
英文名称： Anti-alpha 2 Macroglobulin/FITC
产品编号： YB--9505R-FITC
产品价格： null
产品产地： 中国/美国
品牌商标： Ybscience
更新时间： 2023-08-17T10:24:20
使用范围： 科研使用
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Anti-alpha 2 Macroglobulin/FITC Conjugated抗体
| 产品编号 | YB-9505R-FITC |
| 英文名称 | Anti-alpha 2 Macroglobulin/FITC |
| 中文名称 | FITC标记的α2巨球蛋白(α-2M)抗体 |
| 别 名 | A2M; A2MG_HUMAN; Alpha 2 M; Alpha 2M; Alpha-2-M; Alpha-2-macroglobulin; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5; CPAMD5; DKFZp779B086; FWP007; S863 7. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 免疫学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit, |
| 产品应用 | not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 160kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human alpha 2 Macroglobulin |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. [provided by RefSeq, Jul 2008]. Function: Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase. Subunit: Homotetramer; disulfide-linked. Subcellular Location: Secreted Tissue Specificity: Secreted in plasma Similarity: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Database links: Entrez Gene: 2 Human Entrez Gene: 232345 Mouse Entrez Gene: 24153 Rat Omim: 103950 Human SwissProt: P01023 Human SwissProt: Q61838 Mouse SwissProt: P06238 Rat Unigene: 212838 Human Unigene: 30151 Mouse Unigene: 225884 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applicatioNS |