Orail-L2 抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
Orail-L2 抗体

Orail-L2 抗体

商家询价

产品名称： Orail-L2 抗体

英文名称： Orail-L2 Antibody

产品编号： XY14443-1

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

上海信裕生物科技有限公司
  • 联系人 : 徐经理
  • 地址 : 上海市闵行莘庄工业区春东路508号A1-2F
  • 邮编 : 200612
  • 所在区域 : 上海
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 ORAIL-L2 抗体Applications

In-house applications ELISA, WB, IHC     Application not tested? Please see our Guarantee.
Species specificity Human,Mouse,Rat; other species not tested.
Images
Prev1NextView more validation data
  • 14443-1-AP;human spleen tissuehuman spleen tissue were subjected to SDS PAGE followed by western blot with 14443-1-AP(Orail-L2 antibody) at dilution of 1:300
  • 14443-1-AP;human colon cancer tissueImmunohistochemistry of paraffin-embedded human colon cancer tissue slide using 14443-1-AP( Orail-L2 Antibody) at dilution of 1:50 (under 10x lens)
  • 14443-1-AP;human colon cancer tissueImmunohistochemistry of paraffin-embedded human colon cancer tissue slide using 14443-1-AP( Orail-L2 Antibody) at dilution of 1:50 (under 40x lens)
Positive WB detected in Human spleen tissue
Positive IHC detected in Human colon cancer tissue
Recommended dilution WB : 1:200-1:1000
IHC : 1:20-1:200
 ORAIL-L2 抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information
Immunogen Peptide Full name ORAI calcium release-activated calcium modulator 1
Calculated molecular
weight		 35 kDa Observed molecular 
weight		 44 kDa
GenBank accession 
number		 NM_032790 Gene ID (NCBI) 84876
Gene symbol ORAI1 Synonyms  
Background ORAIL-L2 抗体

Store-operated calcium channels (SOCs) play essential functions in various physiological processes. Orai1 (also named CRACM1) is a critical molecular component of SOCs. Orai1 protein is a 35-45 kDa plasma membrane protein with 4 transmembrane domains. Human patients with a severe combinaed immunodeficiency (SCID) syndrome possess point mutations in Orai1 gene. This antibody may be used to block the ion currents mediated by Orai1. ORAIL-L2 抗体

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