PCR Array

内皮细胞生物学PCR芯片可用于研究与血管内皮细胞生物学有关的84个基因的表达。内皮细胞在疾病进展的过程包括炎症、动脉粥样硬化、血管生成和肿瘤起着至关重要的作用。该芯片包含的基因参与血管生成,血管内皮细胞激活和内皮细胞损伤。通过实时定量PCR的方法，研究者即能够利用该芯片简单可靠地同时检测与动脉粥样硬化有关的基因表达。
Angiogenesis: ANGPT1, CCL2 (MCP-1), CCL5 (RANTES), CX3CL1, EDN1, EDNRA, ENG (EVI-1), F3, FASLG (TNFSF6), FGF1, FGF2 (bFGF), FLT1, FN1, HIF1A, HMOX1, IL1B, IL6, ITGA5, ITGAV, ITGB1, ITGB3, KDR, KIT (CD117), KLK3, MMP2, MMP9, NOS3 (eNOS), NPPB, NPR1, PF4, PGF, PLAU (uPA), PTGS2 (COX2), SERPINE1 (PAI-1), SPHK1, TEK (TIE2), THBS1, TYMP, VEGFA. Vasoconstriction & Vasodilation: ACE, AGT, AGTR1, ALOX5, APOE, CALCA, CAV1, CX3CL1, EDN1, EDN2, EDNRA, F2R, HMOX1, ICAM1, NOS3 (eNOS), NPPB, NPR1, PTGIS, PTGS2 (COX2), SOD1. Inflammatory Response: ACE, AGT, AGTR1, ALOX5, APOE, CALCA, CCL2 (MCP-1), CCL5 (RANTES), CX3CL1, EDNRA, F2R, F3, FN1, HIF1A, HMOX1, IL1B, IL6, NPPB, PTGS2 (COX2), SELE, SPHK1, TGFB1, THBS1, TNF, VCAM1. Apoptosis: ANXA5, BAX, BCL2, BCL2L1 (BCL-X), CASP1 (ICE), CASP3, CAV1, CCL2 (MCP-1), CCL5 (RANTES), CFLAR (CASPER), CX3CL1, EDN1, EDNRA, FAS (TNFRSF6), FASLG (TNFSF6), FGF2, HIF1A, HMOX1, IL1B, IL3, IL6, IL7, OCLN, PF4, PTK2, SPHK1, TEK (TIE2), THBS1, TNF, TNFSF10 (TRAIL). Cell Adhesion: ADAM17 (CD156B), AGT, BCL2, CALCA, CDH5, COL18A1 (Endostatin), CX3CL1, ENG (EVI-1), FGF1, FN1, ICAM1, IL1B, ITGA5, ITGAV, ITGB1, ITGB3, KDR, PDGFRA, PECAM1, PLAU (uPA), PLG, PTK2, SELE, SELL (LECAM1), SELPLG (P-selectin), SERPINE1 (PAI-1), TGFB1, THBS1, TNF, VCAM1, VEGFA, VWF. Coagulation: ANXA5, CAV1, EDN1, F2R, F3, FN1, MMP1, PECAM1, PF4, PLAT (tPA), PLAU (uPA), PLG, PROCR, PTK2, SELL (LECAM1), SELPLG (P-selectin), SERPINE1 (PAI-1), TEK (TIE2), TFPI, THBD, THBS1, TIMP1, VWF. Platelet Activation: APOE, CX3CL1, F2R, FN1, IL11, IL6, ITGB3, NOS3 (eNOS), PDGFRA, PECAM1, PF4, PLG, SERPINE1 (PAI-1), SOD1, TGFB1, THBD, THBS1, TIMP1, VEGFA, VWF.