FITC标记的白细胞免疫球蛋白样受体-B抗体
产品名称： FITC标记的白细胞免疫球蛋白样受体-B抗体
英文名称： Anti-LILRB3/CD85a/FITC
产品编号： HZ-2691R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： Flow-Cyt=1:50-200 ICC=1:50-200 IF=1:50-200
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Rabbit Anti-LILRB3/CD85a/FITC Conjugated antibody
FITC标记的白细胞免疫球蛋白样受体-B抗体
| 英文名称 | Anti-LILRB3/CD85a/FITC |
| 中文名称 | FITC标记的白细胞免疫球蛋白样受体-B抗体 |
| 别 名 | CD85 antigen like family member A; CD85a; CD85a antigen; HL9; IL T5; ILT5; Immunoglobulin like transcript 5; Leukocyte immunoglobulin like receptor 3; Leukocyte immunoglobulin like receptor subfamily B (with TM and ITIM domains) member 3; Leukocyte immunoglobulin like receptor subfamily B member 3; LIR 3; LIR3; Gp91; Pirb; MGC138403; Monocyte inhibitory receptor HL9; PIRB; Lilrb3; 16M4; 16M5; 16M6; 6M1; 7M5; PIRB1; PIRB2; PIRB3; PIRB4;PIRB5. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 免疫学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, |
| 产品应用 | Flow-Cyt=1:50-200 ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 67kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human LILRB3 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Function: May act as receptor for class I MHC antigens. Subcellular Location: Membrane; Single-pass type I membrane protein. Tissue Specificity: Detected in monocytes and B-cells. Database links: Entrez Gene: 11025 Human Omim: 604820 Human SwissProt: O75022 Human Unigene: 631592 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
该基因是白细胞免疫球蛋白样受体（LIR）家族的成员，其发现于染色体区19q134的基因簇中。编码的蛋白质属于含有两个或四个细胞外免疫球蛋白域、一个跨膜结构域和两个到四个细胞质免疫受体酪氨酸的抑制基序（ITIMS）的LIR受体亚家族B类。受体在免疫细胞上表达，其中它与抗原呈递细胞上的MHC I类分子结合，并转导抑制免疫应答刺激的负信号。它被认为是控制炎症反应和细胞毒性，以帮助聚焦免疫反应和限制自身反应性。该基因已发现编码不同亚型的多个转录变体。[ RefSeq，JUL 2008 ]