FITC标记的肺表面活性蛋白A抗体
产品名称： FITC标记的肺表面活性蛋白A抗体
英文名称： Anti-SFTPA1/FITC
产品编号： HZ-0770R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围：
上海沪震实业有限公司
- 联系人 : 鲍丽雯
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- 所在区域 : 上海
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Rabbit Anti-SFTPA1/FITC Conjugated antibody
FITC标记的肺表面活性蛋白A抗体
| 英文名称 | Anti-SFTPA1/FITC |
| 中文名称 | FITC标记的肺表面活性蛋白A抗体 |
| 别 名 | SP-A; SFTPA2; SFTPA1; Surfactant Protein A; pulmonary surfactant-associated glycoprotein A; Pulmonary surfactant-associated protein A2 precursor; SP-A1; SP-A2; SP-A; PSP-A; PSPA; Alveolar proteinosis protein; 35 kDa pulmonary surfactant-associated protein; MGC133365; Pulmonary surfactant apoprotein; Pulmonary surfactant associated protein; SFTP1; SFTPA; SFTPA1B; SP A; SP A1; Surfactant pulmonary associated protein A1; PSPA; SPA2; SFTP1; SPAII; COLEC5; SFTPA2B; SFTA1_HUMAN; SFPA2_HUMAN; Pulmonary surfactant-associated protein A1; Pulmonary surfactant-associated protein A2. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 细胞生物 免疫学 信号转导 细胞表面分子 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, |
| 产品应用 | not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 25kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human SFTPA2/SFTPA1 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: This gene is one of several genes encoding pulmonary-surfactant associated proteins (SFTPA) located on chromosome 10. Mutations in this gene and a highly similar gene located nearby, which affect the highly conserved carbohydrate recognition domain, are associated with idiopathic pulmonary fibrosis. The current version of the assembly displays only a single centromeric SFTPA gene pair rather than the two gene pairs shown in the previous assembly which were thought to have resulted from a duplication. [provided by RefSeq, Sep 2009] Function: In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air-liquid interface in the alveoli of the mammalian lung and is essential for normal respiration. Subunit: Oligomeric complex of 6 set of homotrimers. Subcellular Location: Secreted, extracellular space, extracellular matrix. Secreted, extracellular space, surface film. DISEASE: Defects in SFTPA2 are a cause of pulmonary fibrosis idiopathic (IPF) [MIM:178500]. Pulmonary fibrosis is a lung disease characterized by shortness of breath, radiographically evident diffuse pulmonary infiltrates, and varying degrees of inflammation and fibrosis on biopsy. It results in acute lung injury with subsequent scarring and endstage lung disease. Similarity: Belongs to the SFTPA family. Contains 1 C-type lectin domain. Contains 1 collagen-like domain. Database links: Entrez Gene: 610540 Dog Entrez Gene: 653509 Human Omim: 178630 Human SwissProt: P06908 Dog SwissProt: Q8IWL2 Human Unigene: 535295 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 肺泡表面活性物质A（SP-A）属糖结合蛋白家族,参与肺泡表面活性膜的形成和代谢,除在Ⅱ型细胞中强烈表达外，在细支气管、支气管上皮内也有灶性表达 |
该基因是编码位于10号染色体上的肺表面活性物质相关蛋白（SFTPA）的几个基因之一。该基因和位于附近的高度相似的基因突变影响高度保守的碳水化合物识别结构域，与特发性肺纤维化相关。该组合的当前版本仅显示单个着丝粒SFTPA基因对，而不是先前组合中显示的被认为由复制导致的两个基因对。[ RefSeq，SEP 2009提供]