FITC标记的三磷酸腺苷受体P2X5抗体
产品名称： FITC标记的三磷酸腺苷受体P2X5抗体
英文名称： Anti-P2RX5/FITC
产品编号： HZ-12108R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-P2RX5/FITC Conjugated antibody
FITC标记的三磷酸腺苷受体P2X5抗体
| 英文名称 | Anti-P2RX5/FITC |
| 中文名称 | FITC标记的三磷酸腺苷受体P2X5抗体 |
| 别 名 | ATP receptor; ATP receptor subunit; Ionotropic ATP receptor P2X5; LRH 1; LRH1; Lymphoid restricted histocompatibility antigen 1; MGC47755; P2rx5; P2RX5_HUMAN; P2X purinoceptor 5; P2X5; P2X5R; Purinergic receptor; Purinergic receptor P2X ligand gated ion channel 5; Purinergic receptor P2X5. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 神经生物学 细胞凋亡 通道蛋白 细胞膜受体 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 47kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human P2RX5 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: The P2X receptor family is comprised of ligand-gated ion channels that allow for the increased permeability of calcium into the cell in response to extracellular ATP. The seven P2X receptors, P2X1-P2X7, form either homomeric or heteromeric channels or both. They are characterized by intracellular amino- and carboxy-termini. P2X receptors are expressed in a wide variety of tissues, including neurons, prostate, bladder, pancreas, colon, testis and ovary. The major function of the P2X receptors is to mediate synaptic transmissions between neurons and to other tissues via the binding of extracellular ATP, which acts as a neurotransmitter. The P2X receptors may be involved in the onset of necrosis or apoptosis after prolonged exposure to high concentrations of extracellular ATP. Function: Receptor for ATP that acts as a ligand-gated ion channel. Subunit: Functional P2XRs are organized as homomeric and heteromeric trimers Subcellular Location: Membrane; Multi-pass membrane protein. Tissue Specificity: Expressed at high levels in brain and immune system. Similarity: Belongs to the P2X receptor family. Database links: Entrez Gene: 5026 Human Entrez Gene: 94045 Mouse Entrez Gene: 113995 Rat Omim: 602836 Human SwissProt: Q93086 Human SwissProt: P51578 Rat Unigene: 408615 Human Unigene: 731607 Human Unigene: 156893 Mouse Unigene: 10257 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
P2X受体家族由配体门控离子通道组成，该离子通道允许响应于细胞外ATP而增加钙进入细胞的渗透性。七个P2X受体，P2X1-P2X7，形成同型或异型通道或两者兼而有之。它们的特征是细胞内的氨基和carboxy termini。P2X受体在多种组织中表达，包括神经元、前列腺、膀胱、胰腺、结肠、睾丸和卵巢。P2X受体的主要功能是通过细胞外ATP的结合来介导神经元和其他组织之间的突触传递，ATP作为神经递质。P2X受体可能参与了长期暴露于高浓度细胞外ATP后细胞坏死或凋亡的发生。