FITC标记的7号染色体开放阅读框27抗体
产品名称： FITC标记的7号染色体开放阅读框27抗体
英文名称： Anti-C7orf27/FITC
产品编号： HZ-9542R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-C7orf27/FITC Conjugated antibody
FITC标记的7号染色体开放阅读框27抗体
| 产品编号 | bs-9542R-FITC |
| 英文名称 | Anti-C7orf27/FITC |
| 中文名称 | FITC标记的7号染色体开放阅读框27抗体 |
| 别 名 | BAAT 1; BAAT1; BRAT-1; brat1; BRAT1_HUMAN; BRCA1-associated ATM activator 1; BRCA1-associated protein required for ATM activation protein 1; BRCA1-associated protein required for ATM activation-1; C7orf27; chromosome 7 open reading frame 27; HEAT repeat containing protein C7orf27. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 免疫学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 88kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human BAAT1/C7orf27 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | Function: Required for activation of ATM following ionizing radiation. May act by regulating dephosphorylation of ATM. Subunit: Interacts with BRCA1 and ATM. Subcellular Location: Nucleus. Present at double strand breaks (DSBs) following ionizing radiation treatment. Tissue Specificity: Ubiquitously expressed. DISEASE: Defects in BRAT1 are the cause of rigidity and multifocal seizure syndrome, lethal neonatal (RMFSL) [MIM:614498]. A lethal, neonatal, neurologic disorder characterized by episodic jerking that is apparent in utero, lack of psychomotor development, axial and limb rigidity, frequent multifocal seizures, and dysautonomia. At birth, affected individuals have small heads, overlapping cranial sutures, small or absent fontanels, and depressed frontal bones. Infants show poorly responsive focal jerks of the tongue, face and arms in a nearly continuous sequence throughout life. Similarity: Contains 2 HEAT repeats. Database links: Entrez Gene: 221927 Human Entrez Gene: 231841 Mouse SwissProt: Q6PJG6 Human SwissProt: Q8C3R1 Mouse SwissProt: D3ZUM1 Rat Unigene: 520623 Human Unigene: 271932 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
电离辐射激活ATM所需的。可通过调节ATM的去磷酸化来发挥作用