FITC标记的细胞表面趋化因子受体5抗体
产品名称： FITC标记的细胞表面趋化因子受体5抗体
英文名称： Anti-CXCR5/FITC
产品编号： HZ-3598R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： KLH conjugated synthetic peptide derived from human CXCR5/CD185
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Rabbit Anti-CXCR5/FITC Conjugated antibody
FITC标记的细胞表面趋化因子受体5抗体
| 英文名称 | Anti-CXCR5/FITC |
| 中文名称 | FITC标记的细胞表面趋化因子受体5抗体 |
| 别 名 | BLR 1; BLR1; Burkitt lymphoma receptor 1; Burkitt lymphoma receptor 1 GTP binding protein; C X C chemokine receptor type 5; C-X-C chemokine receptor type 5; CD 185; CD185; CD185 antigen; Chemokine C X C motif receptor 5; Chemokine CXC motif receptor 5; Chemokine receptor 5; CXC chemokine receptor type 5; CXC R5; CXC-R5; CXCR 5; CXCR-5; Cxcr5; CXCR5_HUMAN; MDR 15; MDR-15; MDR15; MGC117347; Monocyte derived receptor 15; Monocyte-derived receptor 15. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 细胞生物 免疫学 信号转导 趋化因子 G蛋白偶联受体 b-淋巴细胞 G蛋白信号 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Pig, Cow, Rabbit, |
| 产品应用 | not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 42kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human CXCR5/CD185 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: The CXCR5 gene was identified as a gene specifically expressed in Burkitt's lymphoma and lymphatic tissues. CXCR5 protein is predicted to be a seven transmembrane G protein coupled receptor and belongs to the CXC chemokine receptor family. BLC, a B lymphocyte chemoattractant, was identified to be a specific ligand for this receptor. Studies of the gene and its mouse conterpart strongly suggest the essential function of the protein is in B cell migration and localization within specific anatomic compartments, such as follicles in lymph nodes as well as in spleen. Function: Cytokine receptor that binds to B-lymphocyte chemoattractant (BLC). Involved in B-cell migration into B-cell follicles of spleen and Peyer patches but not into those of mesenteric or peripheral lymph nodes. May have a regulatory function in Burkitt lymphoma (BL) lymphomagenesis and/or B-cell differentiation. Subcellular Location: Cell membrane; Multi-pass membrane protein. Tissue Specificity: Expression in mature B-cells and Burkitt lymphoma cells. Similarity: Belongs to the G-protein coupled receptor 1 family. Database links: Entrez Gene: 643 Human Entrez Gene: 12145 Mouse Entrez Gene: 29363 Rat Omim: 601613 Human SwissProt: P32302 Human SwissProt: Q04683 Mouse SwissProt: P34997 Rat Unigene: 113916 Human Unigene: 490637 Mouse Unigene: 6246 Mouse Unigene: 120732 Rat Unigene: 127121 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
CXCR5基因是在Burkitt淋巴瘤和淋巴组织中特异表达的基因。CXCR5蛋白是一种七跨膜G蛋白偶联受体，属于CXC趋化因子受体家族。B淋巴细胞趋化因子BLC是该受体的特异性配体。对该基因及其小鼠的研究表明，该蛋白的基本功能是在特定的解剖室中的B细胞迁移和定位，如淋巴结和脾脏中的卵泡。