RBBP8抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
RBBP8抗体

RBBP8抗体

商家询价

产品名称： RBBP8抗体

英文名称： RBBP8Antibody

产品编号： XY 12624-1-

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

上海信裕生物科技有限公司
  • 联系人 : 徐经理
  • 地址 : 上海市闵行莘庄工业区春东路508号A1-2F
  • 邮编 : 200612
  • 所在区域 : 上海
  • 电话 : 152****8802 点击查看
  • 传真 : 点击查看
  • 邮箱 : shxysw02@163.com
  • 二维码 : 点击查看
进入展台

 RBBP8抗体Applications

In-house applications ELISA, WB     Application not tested? Please see our Guarantee.
Species specificity Human, mouse, rat; other species not tested.
Images
Prev1NextView more validation data
  • 12624-1-AP;mouse testis tissuemouse testis tissue were subjected to SDS PAGE followed by western blot with 12624-1-AP(RBBP8 antibody) at dilution of 1:300
Positive WB detected in Mouse testis tissue, A431 cells, Jurkat cells, Raji cells
Recommended dilution WB : 1:200-1:2000
 RBBP8抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information
Immunogen RBBP8 fusion protein ag3314 Full name Retinoblastoma binding protein 8
Calculated molecular
weight		 103 kDa Observed molecular 
weight		 120kd
GenBank accession 
number		 BC030590 Gene ID (NCBI) 5932
Gene symbol RBBP8 Synonyms RBBP8, CTIP, RBBP 8, DNA endonuclease RBBP8, RIM
Background RBBP8抗体

RBBP8 is an endonuclease that cooperates with the MRE11-RAD50-NBN (MRN) complex in processing meiotic and mitotic double-strand breaks (DSBs) by ensuring both resection and intrachromosomal association of the broken ends. It functions downstream of the MRN complex and ATM, promotes ATR activation and its recruitment to DSBs in the S/G2 phase facilitating the generation of ssDNA. It interacted with BRCA1 to form a complex that regulates CHEK1 activation and controls cell cycle G2/M checkpoints on DNA damage. Also it promotes microhomology-mediated alternative end joining (A-NHEJ) during class-switch recombination and plays an essential role in chromosomal translocations RBBP8抗体

XY312Hu22 分泌性白细胞蛋白酶抑制因子(SLPI)单克隆抗体 Monoclonal Antibody to Secretory Leukocyte Peptidase Inhibitor (SLPI) Homo sapiens (Hukl)

XY313Hu22 整合素α1(ITGα1)单克隆抗体 Monoclonal Antibody to Integrin Alpha 1 (ITGa1) Homo sapiens (Hukl)

XY314Hu22 谷胱甘肽还原酶(GR)单克隆抗体 Monoclonal Antibody to Glutathione Reductase (GR) Homo sapiens (Hukl)

XY316Hu22 前胶原C端蛋白酶增强子1(PCPE1)单克隆抗体 Monoclonal Antibody to Procollagen C Proteinase Enhancer 1 (PCPE1) Homo sapiens (Hukl)

XY317Hu22 穿孔素1(PRF1)单克隆抗体 Monoclonal Antibody to Perforin 1 (PRF1) Homo sapiens (Hukl)

XY319Hu22 微管关联蛋白4(kl4)单克隆抗体 Monoclonal Antibody to Microtubule Associated Protein 4 (kl4) Homo sapiens (Hukl)

XY320Hu22 胸腺基质淋巴细胞生成素(TSLP)单克隆抗体 Monoclonal Antibody to Thymic Strokl Lymphopoietin (TSLP) Homo sapiens (Hukl)

XY323Hu22 钙调磷酸酶(CaN)单克隆抗体 Monoclonal Antibody to Calcineurin (CaN) Homo sapiens (Hukl)

XY326Hu22 神经丝蛋白3(NEF3)单克隆抗体 Monoclonal Antibody to Neurofilament 3 (NEF3) Homo sapiens (Hukl)

XY327Hu22 生长关联蛋白43(GAP43)单克隆抗体 Monoclonal Antibody to Growth Associated Protein 43 (GAP43) Homo sapiens (Hukl)

XY329Hu22 微管关联蛋白2(kl2)单克隆抗体 Monoclonal Antibody to Microtubule Associated Protein 2 (kl2) Homo sapiens (Hukl)

XY330Hu22 黑色素瘤关联ME20(ME20M)单克隆抗体 Monoclonal Antibody to Melanoma Associated ME20 (ME20M) Homo sapiens (Hukl)

XY331Hu22 套膜蛋白(iNV)单克隆抗体 Monoclonal Antibody to Involucrin (iNV) Homo sapiens (Hukl)

XY332Hu22 鸟氨酸脱羧酶(ODC)单克隆抗体 Monoclonal Antibody to Ornithine Decarboxylase (ODC) Homo sapiens (Hukl)

XY336Hu22 保护素(CD59)单克隆抗体 Monoclonal Antibody to Protectin (CD59) Homo sapiens (Hukl)

XY343Hu22 Bcl2关联X蛋白(Bax)单克隆抗体 Monoclonal Antibody to Bcl2 Associated X Protein (Bax) Homo sapiens (Hukl)

XY345Hu22 四旋蛋白30(TSPAN30)单克隆抗体 Monoclonal Antibody to Tetraspanin 30 (TSPAN30) Homo sapiens (Hukl)

XY347Hu22 垂体腺苷酸环化酶激活肽(ADCYAP1)单克隆抗体 Monoclonal Antibody to Adenylate Cyclase Activating Polypeptide 1, Pituitary (ADCYAP1) Homo sapiens (Hukl)

XY348Hu22 腺苷酸环化酶1(ADCY1)单克隆抗体 Monoclonal Antibody to Adenylate Cyclase 1, Brain (ADCY1) Homo sapiens (Hukl)