DNCLI1,胞质动力蛋白轻链中间体1抗体

产品编号HZ-20152R
英文名称DNCLI1
中文名称胞质动力蛋白轻链中间体1抗体
别 名Cytoplasmic dynein 1 light intermediate chain 1; cytosolic; DC1L1_HUMAN; DLC-A; DNCLI1; dync1li1; Dynein cytoplasmic 1 light intermediate chain 1; Dynein cytoplasmic light intermediate polypeptide 1; Dynein light chain A; Dynein light intermediate chain 1; Dynein light intermediate chain 1 cytosolic; FLJ10219; LIC1.
说 明 书0.1ml 0.2ml
研究领域细菌及病毒
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat, Chicken,
DNCLI1,胞质动力蛋白轻链中间体1抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量57kDa
细胞定位细胞浆
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human DNCLI1
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
DNCLI1,胞质动力蛋白轻链中间体1抗体PubMedPubMed
产品介绍background:
DNCLI1 (Cytoplasmic dynein 1 light intermediate chain 1) is a 523 amino acid protein that consists of at least 3 heavy chains, 2 intermediate chains and 8 light chains. DNCLI1 may play a role in binding Dynein heavy chain to chromosomes or membranous organelles and also may regulate Dynein enzymatic activity by associating with heavy chains of the Dynein head.

Function:
Cytomegalovirus (CMV) is a member of the Herpes virus family. Members of this family have a characteristic virion structure. The double stranded DNA genome is contained within an icosahedral capsid which is embedded in a proteinaceous layer (tegument) and surrounded by a lipid envelope that is decorated with virus-specific glycoprotein spikes. The viral genes are co-ordinately expressed in groups at various times after infection. Early viral proteins are expressed in the nucleus of infected cells within 3 to 24 hours of infection prior to the commencement of viral DNA replication. This is followed by expression of the early intermediate genes, which encode enzymes required for viral DNA replication. After 48 to 72 hours, a number of late viral antigens may be demonstrated in the nuclei and cytoplasm of infected cells. Cytomegalovirus strain AD169 is a laboratory-adapted strain and appears to lack a 15kb region of the 200kb genome that is present in clinical isolates. This region contains 19 open reading frames whose functions have yet to be elucidated. AD169 is also unique in that it is unable to enter latency and nearly always assumes lytic growth upon infection.

Gene ID:
51143

DNCLI1,胞质动力蛋白轻链中间体1抗体Database links:
Entrez Gene: 51143 Human
Entrez Gene: 235661 Mouse
Entrez Gene: 252902 Rat
SwissProt: Q9Y6G9 Human
SwissProt: Q8R1Q8 Mouse
SwissProt: Q9QXU8 Rat
Unigene: 529495 Human
Unigene: 128627 Mouse
Unigene: 228621 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.