FITC标记的KIAA1683蛋白抗体
产品名称： FITC标记的KIAA1683蛋白抗体
英文名称： Anti-KIAA1683/FITC
产品编号： HZ-17021R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-KIAA1683/FITC Conjugated antibody
FITC标记的KIAA1683蛋白抗体
| 英文名称 | Anti-KIAA1683/FITC |
| 中文名称 | FITC标记的KIAA1683蛋白抗体 |
| 别 名 | K1683_HUMAN; KIAA1683; Uncharacterized protein KIAA1683. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 128kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human KIAA1683 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: KIAA1683 is a 1,180 amino acid protein that contains six IQ domains, exists as three alternatively spliced isoforms, and is encoded by a gene that maps to human chromosome 19p13.11. Consisting of around 63 million bases with over 1,400 genes, chromosome 19 makes up over 2% of human genomic DNA. Chromosome 19 includes a diversity of interesting genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin superfamily members including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG families, and Fcα receptors. Key genes for eye color and hair color also map to chromosome 19. Peutz-Jeghers syndrome, spinocerebellar ataxia type 6, the stroke disorder CADASIL, hypercholesterolemia and insulin-dependent diabetes have been linked to chromosome 19. Translocations with chromosome 19 and chromosome 14 can be seen in some lymphoproliferative disorders and typically involve the proto-oncogene BCL3. Post-translational modifications: Phosphorylated upon DNA damage, probably by ATM or ATR. DISEASE: Contains 6 IQ domains. Similarity: Contains 6 IQ domains. Database links: Entrez Gene: 80726 Human SwissProt: Q9H0B3 Human Unigene: 313471 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
KIAA1683是一个包含六个IQ结构域的1180氨基酸蛋白，作为三个可选择的剪接异构体存在，并且由映射到人类染色体19p13.11的基因编码。由约6300万个碱基组成的1400个以上的基因，19号染色体构成了人类基因组DNA的2%以上。染色体19包括许多有趣的基因，并且被认为是人类染色体上基因密度最大的基因。它是许多免疫球蛋白超家族成员的遗传家园，包括杀伤细胞和白细胞Ig样受体、许多ICAM、CEACAM和PSG家族以及Fcα受体。眼睛颜色和头发颜色的关键基因也映射到19号染色体上。Peutz-Jeghers综合征，脊髓小脑性共济失调6型，中风病CADASIL，高胆固醇血症和胰岛素依赖型糖尿病都与染色体19有关。在一些淋巴增生性疾病中可以看到19号染色体和14号染色体的易位，典型地涉及原癌基因BCL3。