FITC标记的EFCAB6蛋白抗体
产品名称： FITC标记的EFCAB6蛋白抗体
英文名称： Anti-EFCAB6/FITC
产品编号： HZ-
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
上海沪震实业有限公司
- 联系人 : 鲍丽雯
- 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
- 邮编 : 200612
- 所在区域 : 上海
- 电话 : 139****0749 点击查看
- 传真 : 点击查看
- 邮箱 : www.shzbio.net
- 二维码 : 点击查看
Rabbit Anti-EFCAB6/FITC Conjugated antibody
FITC标记的EFCAB6蛋白抗体
| 英文名称 | Anti-EFCAB6/FITC |
| 中文名称 | FITC标记的EFCAB6蛋白抗体 |
| 别 名 | DJBP; CAP binding protein complex interacting protein 1; DJ1 binding protein; DJBP; EFCB6_HUMAN; EF hand calcium binding domain 6; FLJ23588. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 信号转导 转录调节因子 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Chicken, Dog, Cow, Horse, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 173kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human EFCAB6 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: This gene encodes a protein which directly binds the oncogene DJ-1 and androgen receptor to form a ternary complex in cells. This binding protein recruits histone-deacetylase complexes in order to repress transcription activity of androgen receptor. This protein may also play a role in spermatogenesis and fertilization. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011] Function: Negatively regulates the androgen receptor by recruiting histone deacetylase complex, and protein DJ1 antagonizes this inhibition by abrogation of this complex. Six named isoforms produced by alternative splicing. Subunit: Binds PARK7. Part of a ternary complex containing PARK7, EFCAB6/DJBP and AR. Subcellular Location: Nucleus. Tissue Specificity: Specifically expressed in the testis. Similarity: Contains 17 EF-hand domains. Database links: Entrez Gene: 64800 Human SwissProt: Q5THR3 Human Unigene: 658996 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
该基因编码一个直接结合癌基因DJ-1和雄受体的蛋白质，在细胞中形成三元复合物。这种结合蛋白招募组蛋白去乙酰化酶复合体，以抑制雄受体的转录活性。这种蛋白质也可能在精子发生和受精中发挥作用。该基因已发现编码不同亚型的多个转录变体。[ RefSeq，SEP 2011提供]