FITC标记的PCID2蛋白抗体
产品名称： FITC标记的PCID2蛋白抗体
英文名称： Anti-PCID2/FITC
产品编号： HZ-9034R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
上海沪震实业有限公司
- 联系人 : 鲍丽雯
- 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
- 邮编 : 200612
- 所在区域 : 上海
- 电话 : 139****0749 点击查看
- 传真 : 点击查看
- 邮箱 : www.shzbio.net
- 二维码 : 点击查看
Rabbit Anti-PCID2/FITC Conjugated antibody
FITC标记的PCID2蛋白抗体
| 产品编号 | bs-9034R-FITC |
| 英文名称 | Anti-PCID2/FITC |
| 中文名称 | FITC标记的PCID2蛋白抗体 |
| 别 名 | CSN12 like protein; FLJ11305; PCI domain containing protein 2; PCID2_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 免疫学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 46kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human PCID2 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. May favor virus entry in case of infection with herpes simplex virus 1 (HSV1) or herpes simplex virus 2 (HSV2). Function: Required for B-cell survival through the regulation of the expression of cell-cycle checkpoint MAD2L1 protein during B cell differentiation (By similarity). Similarity: Belongs to the CSN12 family. Contains 1 PCI domain. Database links: Entrez Gene: 55795 Human Entrez Gene: 234069 Mouse Entrez Gene: 361182 Rat Omim: 613713 Human SwissProt: Q2TBN6 Cow SwissProt: Q5JVF3 Human SwissProt: Q8BFV2 Mouse Unigene: 741363 Human Unigene: 103427 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
真核翻译起始因子3（EIF-3）复合物的组成部分，这是蛋白质合成起始过程中的几个步骤所必需的。EIF-3复合物与40S核糖体结合，促进EIF-1、EIF-1A、EIF-2：GTP：甲硫基-TrNi和EIF-5的形成，形成43S前起始复合体（43S PIC）。EIF-3复合物刺激mRNA的募集至43S PIC，并扫描mRNA的AUG识别。EIF-3复合物还需要拆解和回收后终止核糖体复合体，并随后防止在启动前440和60S核糖体亚基的过早加入。在感染单纯疱疹病毒1（HSV1）或单纯疱疹病毒2（HSV2）的情况下，可能有利于病毒进入。