KCNE1L,钾离子通道蛋白家族成员1样蛋白抗体

产品编号HZ-9929R
英文名称KCNE1L
中文名称钾离子通道蛋白家族成员1样蛋白抗体
别 名AMME syndrome candidate gene 2 protein; AMMECR2 protein; Cardiac voltage gated potassium channel accessory subunit 5; KCNE1 like; KCNE5; Mink; MinK like protein; Potassium voltage gated channel subfamily E member 1 like protein; Potassium voltage gated channel, Isk related family, member 1 like; Voltage gated potassium channel accessory subunit 5; KCE1L_HUMAN.
说 明 书0.1ml 0.2ml
研究领域心血管 神经生物学 通道蛋白
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat, Pig, Cow, Rabbit, Sheep,
KCNE1L,钾离子通道蛋白家族成员1样蛋白抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量15kDa
细胞定位细胞浆 细胞膜
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human KCNE1L
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
KCNE1L,钾离子通道蛋白家族成员1样蛋白抗体PubMedPubMed
产品介绍background:
KCNE1L belongs to the potassium channel KCNE family which represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume.

Subcellular Location:
Plasma membrane; Single-pass type I membrane protein.

Tissue Specificity:
Highly expressed in heart, skeletal muscle, brain, spinal cord and placenta.

DISEASE:
Defects in KCNE1L are involved in Alport syndrome with mental retardation midface hypoplasia and elliptocytosis (ATS-MR) [MIM:300194]. A X-linked contiguous gene deletion syndrome characterized by glomerulonephritis, deafness, mental retardation, midface hypoplasia and elliptocytosis.

Similarity:
Belongs to the potassium channel KCNE family.

Database links:
Entrez Gene: 23630 Human
Omim: 300328 Human
SwissProt: Q9UJ90 Human

KCNE1L,钾离子通道蛋白家族成员1样蛋白抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.